Xifaxan Price (rifaximin)

Xifaxan price by strength

Cheapest ways to get Xifaxan 550 mg

The cheapest ways we found to get brand Xifaxan 550 mg (prices checked Nov 11, 2026). The lowest 90-day cost is shaded green.

Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.

How much does Xifaxan cost without insurance?

Without insurance, Xifaxan costs $4,034.48 for a 30-day supply at the U.S. list price, or about $12,103.44 for 90 days. Licensed pharmacies abroad charged from $1,579.99 for 90 days of brand Xifaxan 550 mg in our latest check (Nov 11, 2026), shipping included.

Xifaxan cost with Medicare

In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Xifaxan depends on your plan's drug list and your coverage phase. Starting January 1, 2027, Medicare will pay a negotiated price of $1,000 for a 30-day supply of Xifaxan (CMS, checked Oct 30, 2026). That's what Medicare will pay, not your copay. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.

Xifaxan cost with insurance

With private or employer insurance, what you pay for Xifaxan depends on your plan's drug list, deductible and copay. As little as $0 with the Xifaxan copay program for eligible patients with coverage for Xifaxan. Maximum benefits apply (Salix).

Medicaid: You may qualify for the Bausch Health Patient Assistance Program (Bausch Health).

Xifaxan patient assistance program

Yes. Xifaxan is offered through Bausch Health Patient Assistance Program, which can give the medicine at no cost to people who qualify. Who qualifies: Bausch says Medicaid patients whose plans no longer cover its products may be eligible for Xifaxan through its PAP; other rules are on the program site. How to apply: Enroll at bauschhealthpap.com or call 1-833-862-8727. (Checked 2026-10-29.)

Xifaxan FAQ

Brand vs. generic: cost for 90 days

Lowest in this comparison: Brand Xifaxan 550 mg from licensed pharmacies abroad.

90 days = 180 tablets of 550 mg. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.

Savings programs from the maker

eDrugSearch does not offer its own Xifaxan coupons. These are the real savings programs, run by the drug's maker and by Medicare:

• Xifaxan Savings Card: for people with private or employer insurance that covers Xifaxan. Eligible patients may pay as little as $0. Not for Medicare, Medicaid, Medigap, VA, DOD or TRICARE, and not for people paying full cash. Maximum benefits apply. Call 1-866-943-2926 (1-866-XIFAXAN), option 1. (Xifaxan savings)
• Bausch Health Patient Assistance Program: for Medicaid patients whose plans no longer cover Bausch Health products, who may be able to get Xifaxan. Bausch Health and Salix left the Medicaid drug rebate program on October 1, 2025. Call 1-833-862-8727. (Bausch Health PAP)
• Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
• Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

What is Xifaxan used for?

Xifaxan (rifaximin) is an antibiotic that works mainly in the gut. According to its FDA label (DailyMed), it is used to:

• Lower the risk of overt hepatic encephalopathy (HE) coming back in adults. HE is confusion and other brain changes caused by serious liver disease.
• Treat irritable bowel syndrome with diarrhea (IBS-D) in adults.
• Treat travelers' diarrhea caused by certain E. coli bacteria in adults and children 12 and older. It should not be used when diarrhea comes with fever or blood in the stool.

Xifaxan comes as 200 mg and 550 mg tablets. The FDA label lists different schedules for each use: 550 mg two times a day for HE (ongoing), 550 mg three times a day for 14 days for IBS-D (a course that can be repeated up to two times if symptoms come back), and 200 mg three times a day for 3 days for travelers' diarrhea. That is why our 90-day cost uses 2 tablets of 550 mg a day, and why an IBS-D course costs less. Your prescriber decides which medicine is right for you.