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Prilosec Price, Coupons and Generic
- Lowest U.S. online pharmacy price
- Not available
- Lowest international online pharmacy price
- $1.50 per daily dose$144.95 for 90 days (90 daily doses), shipping included · brand Prilosec 20 mg, not FDA-approved · ships from Canada
FDA-approved generic omeprazole 20 mg from $18.50 for 90 days at U.S. pharmacies
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Quick answerAs of Nov 3, 2026, brand Prilosec 20 mg (sold abroad as Losec) costs from $144.95 for 90 days at licensed pharmacies abroad we compared. Brand Prilosec capsules are no longer sold in the U.S., but FDA-approved generic omeprazole is, and Prilosec OTC 20 mg is sold without a prescription.
Name check: Prilosec OTC (20 mg tablets for frequent heartburn) is sold without a prescription and isn't priced here. Abroad, brand Prilosec capsules are sold as Losec.
Compare Prilosec prices from licensed online pharmacies
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per daily doseLicensed U.S. pharmacy A | Omeprazole DR 20 mg Capsules20 mg · genericMaker listed by pharmacy: Xiromed, LLCShips from United StatesShips within the U.S. (no customs) · checked Nov 4, 2026 | $13.50for 90 daily doses$0.15 per daily dose | $5Pharmacy's estimate: 2–8 business days | $18.50 for 90 days= $18.50 for 90 daysincl. $5 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseLicensed U.S. pharmacy A | Omeprazole DR 10 mg Capsules10 mg · genericMaker listed by pharmacy: Glenmark Pharmaceuticals Inc., USAShips from United StatesShips within the U.S. (no customs) · checked Nov 4, 2026 | $17.10for 90 daily doses$0.19 per daily dose | $5Pharmacy's estimate: 2–8 business days | $22.10 for 90 days= $22.10 for 90 daysincl. $5 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseLicensed U.S. pharmacy A | Omeprazole DR 40 mg Capsules40 mg · genericMaker listed by pharmacy: Glenmark Pharmaceuticals Inc., USAShips from United StatesShips within the U.S. (no customs) · checked Nov 4, 2026 | $18for 90 daily doses$0.20 per daily dose | $5Pharmacy's estimate: 2–8 business days | $23 for 90 days= $23 for 90 daysincl. $5 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy B | Generic Equivalent To Prilosec 20mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.20 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Dr Reddy's | $4.41per 30 daily doses · 3 packs = $13.23$0.15 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $28.18 for 90 days= $28.18 for 90 daysincl. $14.95 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy C | Generic Equivalent To Prilosec 20mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.20 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Dr Reddy's | $5.67per 30 daily doses · 3 packs = $17.01$0.19 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $31.96 for 90 days= $31.96 for 90 daysincl. $14.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy D | Generic Equivalent to Prilosec 40mg (tablet; U.S. generic is a capsule)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Dr. Reddy's | $24.90for 90 daily doses$0.28 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $39.85 for 90 days= $39.85 for 90 daysincl. $14.95 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy B | Generic Equivalent To Prilosec 40mg (tablet; U.S. generic is a capsule)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Dr. Reddy's | $25.76for 90 daily doses$0.29 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $40.71 for 90 days= $40.71 for 90 daysincl. $14.95 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy B | Generic Equivalent To Prilosec 10mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Ranbaxy Laboratories | $28.10for 90 daily doses$0.31 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $43.05 for 90 days= $43.05 for 90 daysincl. $14.95 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy D | Generic Equivalent to Prilosec 10mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Ranbaxy Laboratories | $29.07for 90 daily doses$0.32 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $44.02 for 90 days= $44.02 for 90 daysincl. $14.95 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy C | Generic Equivalent To Prilosec 40mg (tablet; U.S. generic is a capsule)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Dr. Reddy's | $31.77for 90 daily doses$0.35 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $46.72 for 90 days= $46.72 for 90 daysincl. $14.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy C | Generic Equivalent To Prilosec 10mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Ranbaxy Laboratories | $32.94for 90 daily doses$0.37 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $47.89 for 90 days= $47.89 for 90 daysincl. $14.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy E | Omeprazole 10mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.10 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Dr Reddy's Laboratories Ltd | $38.33for 90 daily doses$0.43 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $53.28 for 90 days= $53.28 for 90 daysincl. $14.95 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy E | Omeprazole 20mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.20 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Dr Reddy's Laboratories Ltd | $21.22per 40 daily doses · 2 packs = $42.44$0.53 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $57.39 for 80 days= $64.56 for 90 daysWorked out from an 80-day orderChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy D | Generic Equivalent to Prilosec 20mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.20 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Dr Reddy's | $53.28for 90 daily doses$0.59 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $68.23 for 90 days= $68.23 for 90 daysincl. $14.95 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy E | Omeprazole 40mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Dr Reddy's Laboratories Ltd | $19.24per 30 daily doses · 3 packs = $57.72$0.64 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $72.67 for 90 days= $72.67 for 90 daysincl. $14.95 shippingChecked Nov 4 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy F | PRILOSEC 40MG CAPSULE 90 (GENERIC OMEPRAZOLE FROM INDIA)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.40 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: DR REDDYS | $59for 90 daily doses$0.66 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $73.95 for 90 days= $73.95 for 90 daysincl. $14.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy G | Prilosec 10mg (New Zealand Losec capsule; U.S. brand capsules are discontinued)10 mg · brand · Filled in New ZealandMaker listed by pharmacy: AstraZeneca | $135for 90 daily doses$1.50 per daily dose | $9.95Pharmacy's estimate: 4–6 weeks | $144.95 for 90 days= $144.95 for 90 daysincl. $9.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy G | Prilosec 20mg (Canadian Losec capsule; U.S. brand capsules are discontinued)20 mg · brand · Filled in CanadaMaker listed by pharmacy: AstraZeneca | $135for 90 daily doses$1.50 per daily dose | $9.95Pharmacy's estimate: 4–6 weeks | $144.95 for 90 days= $144.95 for 90 daysincl. $9.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy F | PRILOSEC 10MG CAPSULE 90 (LOSEC BRAND FROM NEW ZEALAND) (New Zealand Losec capsule; U.S. brand capsules are discontinued)10 mg · brand · Filled in New ZealandMaker listed by pharmacy: ASTRAZENECA | $130for 90 daily doses$1.44 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $144.95 for 90 days= $144.95 for 90 daysincl. $14.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy H | Losec 10mg Capsule (Delayed Release) (New Zealand Losec capsule; U.S. brand capsules are discontinued)10 mg · brand · Filled in New ZealandMaker listed by pharmacy: Astrazeneca | $152.79for 90 daily doses$1.70 per daily dose | FreePharmacy's estimate: 2–3 weeks | $152.79 for 90 days= $152.79 for 90 daysincl. $0 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy G | Prilosec 20mg (New Zealand Losec capsule; U.S. brand capsules are discontinued)20 mg · brand · Filled in New ZealandMaker listed by pharmacy: AstraZeneca | $145for 90 daily doses$1.61 per daily dose | $9.95Pharmacy's estimate: 4–6 weeks | $154.95 for 90 days= $154.95 for 90 daysincl. $9.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy H | Losec 20mg Capsule (Delayed Release) (New Zealand Losec capsule; U.S. brand capsules are discontinued)20 mg · brand · Filled in New ZealandMaker listed by pharmacy: Astrazeneca | $167.47for 90 daily doses$1.86 per daily dose | FreePharmacy's estimate: 2–3 weeks | $167.47 for 90 days= $167.47 for 90 daysincl. $0 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy F | PRILOSEC 20MG CAPSULE 90 (LOSEC BRAND FROM NEW ZEALAND) (New Zealand Losec capsule; U.S. brand capsules are discontinued)20 mg · brand · Filled in New ZealandMaker listed by pharmacy: ASTRAZENECA | $161for 90 daily doses$1.79 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $175.95 for 90 days= $175.95 for 90 daysincl. $14.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy H | Losec 40mg Capsule (Delayed Release) (New Zealand Losec capsule; U.S. brand capsules are discontinued)40 mg · brand · Filled in New ZealandMaker listed by pharmacy: Astrazeneca | $193.74for 90 daily doses$2.15 per daily dose | FreePharmacy's estimate: 2–3 weeks | $193.74 for 90 days= $193.74 for 90 daysincl. $0 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy F | PRILOSEC 40MG CAPSULE 90 (LOSEC BRAND FROM NEW ZEALAND) (New Zealand Losec capsule; U.S. brand capsules are discontinued)40 mg · brand · Filled in New ZealandMaker listed by pharmacy: ASTRAZENECA | $180for 90 daily doses$2.00 per daily dose | $14.95Pharmacy's estimate: 4–6 weeks | $194.95 for 90 days= $194.95 for 90 daysincl. $14.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseLicensed Canadian pharmacy I | Losec 20mg (Canadian Losec capsule; U.S. brand capsules are discontinued)20 mg · brand · Filled in CanadaMaker listed by pharmacy: CHEPLAPHARM ARZNEIMITTEL GMBH | $213.33for 90 daily doses$2.37 per daily dose | $9.95Pharmacy's estimate: 3–6 weeks | $223.28 for 90 days= $223.28 for 90 daysincl. $9.95 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy H | Losec 20mg Capsule (Delayed Release) (Canadian Losec capsule; U.S. brand capsules are discontinued)20 mg · brand · Filled in CanadaMaker listed by pharmacy: Astra-Zeneca Canada Inc. | $239.24for 90 daily doses$2.66 per daily dose | FreePharmacy's estimate: 2–3 weeks | $239.24 for 90 days= $239.24 for 90 daysincl. $0 shippingChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy F | PRILOSEC 20MG CAPSULE 100 (GENERIC OMEPRAZOLE FROM INDIA)Not FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.20 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: DR REDDYS | $39for 100 daily doses$0.39 per daily doseOver 3-month supply | $14.95Pharmacy's estimate: 4–6 weeks | $53.95 for 100 days= $48.56 for 90 daysWorked out from a 100-day orderChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy G | Omeprazole 20mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.20 mg · generic · Filled in CanadaMaker listed by pharmacy: Apotex Inc | $85for 100 daily doses$0.85 per daily doseOver 3-month supply | $9.95Pharmacy's estimate: 4–6 weeks | $94.95 for 100 days= $85.46 for 90 daysWorked out from a 100-day orderChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
| Lowest per daily doseOnline pharmacy F | PRILOSEC 40MG CAPSULE 180 (LOSEC BRAND FROM NEW ZEALAND) (New Zealand Losec capsule; U.S. brand capsules are discontinued)40 mg · brand · Filled in New ZealandMaker listed by pharmacy: ASTRAZENECA | $217.50for 180 daily doses$1.21 per daily doseOver 3-month supply | $14.95Pharmacy's estimate: 4–6 weeks | $232.45 for 180 days= $116.23 for 90 daysWorked out from an 180-day orderChecked Nov 3 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Prilosec from Canada?
90-day cost = 90 daily doses at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 3, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards.
Members see pharmacy names, ratings, visit links and price-drop alerts.
Join to See PharmaciesAlready a member? Sign inPrilosec price by strength
| Strength | Lowest brand90 days | Lowest generic abroad90 days, not FDA-approved | Price per daily dose |
|---|---|---|---|
| Prilosec 10 mg | $144.95 | $43.05 | $1.50 brand · $0.31 generic |
| Prilosec 20 mg | $144.95 | $28.18 | $1.50 brand · $0.15 generic |
| Prilosec 40 mg | $193.74 | $39.85 | $2.15 brand · $0.28 generic |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per daily dose is for that lowest pack, before shipping. Prices checked Nov 3, 2026.
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90-day prices from 8 licensed pharmacies abroad shipping to the U.S.: $28.18 to $239.24, any strength, shipping included.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Prilosec · Similar drugs · Uses · FAQ
Prilosec (omeprazole) for acid reflux and ulcers. Brand capsules are sold abroad as Losec. In the U.S., there's generic omeprazole and Prilosec OTC.
Prilosec cost at a glance
- Generic Prilosec is sold in the U.S. The FDA has approved generic omeprazole delayed-release capsules (10, 20 and 40 mg) from many companies, rated equivalent to Prilosec (FDA Orange Book). The 2026 Texas drug price filing lists 30 capsules of generic omeprazole 20 mg at $3.36 (Glenmark) and $4.20 (Dr. Reddy's) (Texas DSHS).
- Brand Prilosec capsules are discontinued in the U.S. The FDA lists Prilosec 10, 20 and 40 mg capsules as discontinued, and in 2016 it found they were not taken off the market for safety or effectiveness reasons (Federal Register). Outside the U.S., the same capsules are sold as Losec.
- No U.S. list price for the brand: because brand Prilosec capsules are discontinued in the U.S., there's no current U.S. list price to compare. FDA-approved generic omeprazole 20 mg lists at $3.36 to $4.20 for 30 capsules in the Texas 2026 drug price filing (Texas DSHS).
- Prilosec OTC: sold without a prescription as 20 mg tablets for frequent heartburn in adults, 1 tablet a day for a 14-day course (Prilosec OTC label). Prices vary by store.
- How we count: 1 capsule or tablet a day at the strength shown. Most adult uses on the U.S. label are 20 mg once a day (FDA label). Some uses have other doses.
- With Medicare: your cost depends on your Part D plan. In 2026, deductibles are capped at $615 and yearly out-of-pocket costs for covered drugs at $2,100 (Medicare.gov).
- From online pharmacies abroad: $144.95 to $239.24 for 90 days of brand Prilosec (Losec) 20 mg and $28.18 to $68.23 for generic omeprazole 20 mg, shipping included (checked Nov 3, 2026).
How much does Prilosec cost in the U.S.?
| If you have | What Prilosec costs | Source |
|---|---|---|
| No insurance (brand Prilosec) | Brand Prilosec capsules are discontinued in the U.S., so there's no current U.S. list price. FDA-approved generic omeprazole capsules are sold (see the next row). | Drugs@FDA |
| No insurance (generic omeprazole) | FDA-approved generic omeprazole capsules (10, 20 and 40 mg) are sold in the U.S. The Texas 2026 filing lists 30 capsules of generic omeprazole 20 mg at $3.36 (Glenmark) and $4.20 (Dr. Reddy's) list price. Ask your pharmacist for the cash price. | Texas DSHS 2026 WAC report |
| Without a prescription (Prilosec OTC) | Prilosec OTC 20 mg tablets are sold over the counter for frequent heartburn in adults, as a 14-day course, in packs of 14, 28 or 42 tablets. Prices vary by store. | DailyMed (Prilosec OTC label) |
| Private or employer insurance | Your copay depends on your plan and whether it covers generic omeprazole, which the FDA rates as equivalent to Prilosec. Ask your plan or pharmacist. | FDA Orange Book |
| Medicare Part D | Your cost depends on your plan's drug list and coverage stage. | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
Brand Prilosec capsules (10, 20 and 40 mg) are no longer sold in the U.S. (Drugs@FDA). FDA-approved generic omeprazole capsules are, and in the Texas 2026 drug price filing, 30 capsules of generic omeprazole 20 mg list at $3.36 (Glenmark) and $4.20 (Dr. Reddy's) (Texas DSHS). Prescription Prilosec packets for oral suspension (2.5 and 10 mg) are a different product and aren't priced on this page.
Prilosec cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100, you pay nothing more for covered drugs for the rest of the year. What you pay for Prilosec or generic omeprazole depends on your plan's drug list.
| Medicare Part D | What Prilosec costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026, you pay nothing more for covered drugs that year. | Medicare.gov |
Prilosec coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
eDrugSearch does not offer its own Prilosec coupons. These are the real savings programs, run by the drug's maker and by Medicare:
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Prilosec?
Yes. The FDA has approved generic omeprazole delayed-release capsules (10, 20 and 40 mg) from many companies, including Dr. Reddy's, Apotex, Aurobindo, Glenmark, Sandoz, Zydus, Lannett and Xiromed, all rated equivalent to Prilosec. The first was approved on November 1, 2002. Dr. Reddy's generic 20 mg has been listed as on the market since January 21, 2009. No generic of the Prilosec 2.5 mg and 10 mg packets is approved. Omeprazole 20 mg is also sold over the counter.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 10 mg | Yes | Dr. Reddy's, Apotex, Aurobindo, Glenmark, Sandoz, Zydus, Lannett, Xiromed and others | — |
| 20 mg | Yes | Dr. Reddy's, Apotex, Aurobindo, Glenmark, Sandoz, Zydus, Lannett, Xiromed and others | — |
| 40 mg | Yes | Dr. Reddy's, Apotex, Aurobindo, Glenmark, Sandoz, Zydus, Lannett, Xiromed and others | — |
Outside the U.S.: Online pharmacies abroad may also sell generic omeprazole made for other markets. Those packs are not FDA-approved, and the price table labels them that way.
Source: FDA Orange Book: omeprazole products. As of Nov 5, 2026.
Compare Prilosec with similar drugs
Other acid reducers in the same class (proton pump inhibitors) that people often compare with Prilosec. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Nexiumesomeprazole | Acid reducer (proton pump inhibitor, or PPI) | $42.57 for 90 days | See prices |
| Dexilantdexlansoprazole | Acid reducer (proton pump inhibitor, or PPI) | $57.41 for 90 days | See prices |
| Aciphexrabeprazole | Acid reducer (proton pump inhibitor, or PPI) | $30.26 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Prilosec used for?
Prilosec (omeprazole) is a proton pump inhibitor, a medicine that lowers stomach acid. According to its FDA label (DailyMed), prescription Prilosec is used:
- To treat active duodenal ulcers (ulcers in the first part of the small intestine) and active benign stomach ulcers, in adults.
- With the antibiotics clarithromycin, or clarithromycin and amoxicillin, to clear H. pylori infection in adults with duodenal ulcer disease and lower the chance the ulcer comes back.
- To treat heartburn and other symptoms of gastroesophageal reflux disease (GERD) in people 1 year and older.
- To heal erosive esophagitis (damage to the food pipe from stomach acid) in people 1 month and older, and to keep it healed in people 1 year and older.
- For conditions where the stomach makes too much acid, such as Zollinger-Ellison syndrome, in adults.
In the U.S., brand Prilosec capsules are discontinued; generic omeprazole comes as 10, 20 and 40 mg delayed-release capsules, and prescription Prilosec is still sold as 2.5 mg and 10 mg packets mixed with water (not priced here). Prilosec OTC, sold over the counter, is only for frequent heartburn in adults. Your prescriber decides which medicine is right for you.
Is it safe to order Prilosec from Canada?
Many Americans do, but U.S. law and customs rules apply, and for Prilosec, compare the U.S. price of FDA-approved generic omeprazole before you order. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, brand Prilosec is sold as Losec 20 mg delayed-release capsules and Losec MUPS 20 mg tablets (Health Canada); in New Zealand, as Losec 10, 20 and 40 mg capsules (Medsafe).
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much is Prilosec without insurance?
Brand Prilosec capsules are no longer sold in the U.S., so there's no U.S. list price to compare. Licensed pharmacies abroad charged from $144.95 for 90 days of brand Prilosec (Losec) 20 mg in our latest check (Nov 3, 2026). In the U.S., the Texas 2026 filing lists 30 capsules of FDA-approved generic omeprazole 20 mg from $3.36. Ask your pharmacist for the cash price.
Is there a generic Prilosec?
Yes. The FDA has approved generic omeprazole delayed-release capsules (10, 20 and 40 mg) from many companies, rated equivalent to Prilosec, and the first was approved in November 2002. The generic name is omeprazole. Ask your pharmacist whether a generic can fill your prescription.
Is Prilosec OTC the same as omeprazole?
Prilosec OTC contains omeprazole: each tablet has 20 mg of omeprazole (as omeprazole magnesium). It's the brand-name over-the-counter version, sold for frequent heartburn in adults as a 14-day course. Store-brand omeprazole 20 mg is also sold over the counter.
Is Prilosec still sold by prescription?
Only as packets. The FDA lists brand Prilosec 10, 20 and 40 mg capsules as discontinued. Prilosec 2.5 mg and 10 mg packets for oral suspension are still sold by prescription, and FDA-approved generic omeprazole capsules are widely available.
Is there a Prilosec coupon or savings card?
Generic omeprazole has very low list prices: 30 capsules of 20 mg list at $3.36 to $4.20 in the Texas 2026 drug price filing. With Medicare and limited income, Extra Help can lower what you pay.
How much does Prilosec cost with Medicare?
It depends on your Part D plan. In 2026, Part D deductibles are capped at $615 and out-of-pocket costs for covered drugs at $2,100 a year. People with limited income can apply for Extra Help.
Is Prilosec taken daily?
Most adult uses on the prescription label are once a day, for a set number of weeks. Prilosec OTC is 1 tablet a day for 14 days, no more often than every 4 months unless a doctor says so. Your prescriber decides which medicine is right for you.
What is Prilosec called in Canada?
In Canada, brand Prilosec is sold as Losec: Losec 20 mg delayed-release capsules and Losec MUPS 20 mg tablets, listed as marketed by Cheplapharm in Health Canada's drug database.
Sources
- Texas DSHS 2026 Annual WAC Report (generic omeprazole 20 mg, 30 capsules: $3.36 (Glenmark, NDC 68462-396-30), $4.20 (Dr. Reddy's))
- Drugs@FDA: PRILOSEC capsules (NDA 019810) (10, 20 and 40 mg capsules discontinued)
- Federal Register: FDA determination (FR Doc. 2016-21227, Sept. 6, 2016) (Prilosec capsules not withdrawn for safety or effectiveness reasons)
- Drugs@FDA: PRILOSEC for delayed-release oral suspension (NDA 022056) (2.5 and 10 mg packets, prescription)
- Drugs@FDA: PRILOSEC OTC (NDA 021229) (over-the-counter)
- PRILOSEC U.S. prescribing information (DailyMed)
- Prilosec OTC Drug Facts label (DailyMed)
- FDA Orange Book: omeprazole products
- Drugs@FDA data: omeprazole generics (ANDAs) (Rx capsules rated AB; first approval Nov. 1, 2002 (ANDA 075410); over-the-counter 20 mg generics)
- FDA NDC Directory: Dr. Reddy's omeprazole 20 mg capsules (marketing start Jan. 21, 2009)
- Health Canada Drug Product Database: LOSEC (DIN 00846503 capsule 20 mg and DIN 02242462 Losec MUPS 20 mg, Marketed (Cheplapharm); checked 2026-11-05)
- Medsafe (New Zealand): Losec capsules data sheet (10, 20 and 40 mg capsules, revised March 2026)
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.