Generic Synthroid (levothyroxine sodium) Price

Levothyroxine price by strength

Levothyroxine names

- Brand name: Synthroid (AbbVie)
- Generic name: levothyroxine sodium
- Names in Canada: Synthroid, plus generics such as Apo-Levothyroxine (Health Canada Drug Product Database, marketed products, checked Oct 29, 2026)
- Other names: Levoxyl (brand, Pfizer); Unithroid (brand, Amneal)

Levothyroxine sodium packs made for other countries are not FDA-approved.

Levothyroxine FAQ

Brand vs. generic: cost for 90 days

Lowest in this comparison: Generic levothyroxine sodium 50 mcg, U.S. pharmacy cash price.

90 days = 90 tablets of 50 mcg. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.

See brand Synthroid prices

Levothyroxine cost with Medicare in 2026

Each Part D plan has its own list of covered drugs and copays, so what you pay for levothyroxine depends on your plan (Medicare Plan Finder). In 2026, Part D plans can have a yearly deductible of up to $615, and your out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027) (Medicare.gov). AbbVie's Synthroid copay card and Synthroid Delivers Program can't be used with Medicare.

Savings programs from the maker

eDrugSearch does not offer its own Levothyroxine coupons. AbbVie's Synthroid copay card, Synthroid Delivers Program and TrumpRx coupon are for brand Synthroid only (see the brand page). These programs can lower what you pay for generic levothyroxine:

• Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
• Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
• Costco Pharmacy member prices: Costco publishes member prices for many prescriptions, for people with a Costco membership. Non-members can also use Costco pharmacies and pay the regular cash price. Member prices can't be used with insurance, Medicare or Medicaid claims. (Costco Pharmacy)
• Amazon Pharmacy Prime and RxPass: Amazon Pharmacy offers Prime members discounts on many prescriptions, and RxPass, for Prime members, covers a set list of generics for a flat monthly fee. Prime is not required to use Amazon Pharmacy. Prime savings have limits for people with Medicare, Medicaid or Tricare, and RxPass is not open to people with Medicaid or CHIP. (Amazon Pharmacy)
• Discount cards: Discount cards (for example GoodRx or SingleCare) may lower the price at local pharmacies; prices vary by pharmacy and ZIP code.

When people choose brand Synthroid

Some people get brand Synthroid instead of generic levothyroxine sodium. Common reasons:

• A prescription marked “dispense as written” (or “brand medically necessary”) tells the pharmacy to fill brand Synthroid, not a generic. State laws set the rules for generic substitution.
• Brand Synthroid has its own cash prices: TrumpRx.gov lists 90 tablets for $56.25 with an AbbVie coupon, and AbbVie's Synthroid Delivers Program mails 90 tablets for $75 (AbbVie). These can't be used with Medicare or Medicaid.
• Some insurance and Medicare drug plans cover the brand and the generic at different copays, or cover only one of them. Your plan's drug list shows which.

Your prescriber decides which medicine is right for you.

Compare prices for your other medicines

• Synthroid prices from $29.12 for 90 days

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength.

What is Levothyroxine used for?

Levothyroxine sodium is a man-made form of the thyroid hormone thyroxine (T4), the same medicine as in Synthroid. The FDA label for Synthroid (DailyMed) lists these uses in adults and children, including newborns:

• As replacement therapy for hypothyroidism (an underactive thyroid), whether present from birth or acquired.
• Along with surgery and radioactive iodine, to suppress TSH (thyroid-stimulating hormone) in certain kinds of thyroid cancer.

Generic levothyroxine tablets come in 25, 50, 75, 88, 100, 112, 125, 137, 150, 175, 200 and 300 mcg, taken once a day, and the dose is set for each person. The label has a boxed warning: thyroid hormones, including levothyroxine, should not be used to treat obesity or for weight loss, and larger doses can cause serious or even life-threatening effects. Check the label that comes with your medicine. Your prescriber decides which medicine is right for you.