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Generic Dificid (fidaxomicin) Price

Yes, FDA-approved generic fidaxomicin is sold in the U.S. As of Nov 11, 2026, it costs from $1,416.84 for one 10-day course at U.S. pharmacies we list.

Lowest U.S. online pharmacy price
$70.33 per tablet$1,416.84 for one 10-day course, shipping included · FDA-approved generic fidaxomicin 200 mg · ships within the U.S.
Lowest international online pharmacy price
Not available

Brand Dificid 200 mg from $2,808.95

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Prices checked Nov 11, 2026 · Page updated November 11, 2026 · By the eDrugSearch team · How we check pharmacies and prices

Name check: Dificid oral suspension (liquid) has no generic and is not priced here. Prices on this page are for one 10-day course, not a monthly supply.

Compare generic Dificid prices

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PharmacyMedicationPriceShipping & deliveryTotalBuy
Licensed U.S. pharmacy AFidaxomicin200 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Oct 29, 2026$1,411.59for 20 tablets$70.58 per tablet$5.25Delivery time not stated$1,416.84 for one 10-day course= $1,416.84 for one 10-day courseincl. $5.25 shippingChecked Oct 29See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy BFidaxomicin, 200 MG Tablet (Prime member price)200 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026$6,746.17for 30 tablets$224.87 per tabletFreePharmacy's estimate: Usually next day$6,746.17 for 135 days= $6,746.17 for one 10-day courseincl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy BFidaxomicin, 200 MG Tablet (price without insurance)200 mg · genericU.S. pharmacy; maker not listed on its price pageShips from United StatesShips within the U.S. (no customs) · checked Nov 11, 2026$7,120.50for 30 tablets$237.35 per tabletFee not publishedPharmacy's estimate: Usually next day$7,120.50 for 135 days= $7,120.50 for one 10-day course+ shippingincl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy

Buying from a pharmacy outside the U.S.? Read Is it safe to order Fidaxomicin from Canada?

Course cost = 20 tablets for one 10-day course, bought as one order of whole packs with one shipping fee. Course cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for one 10-day course; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.

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Jump to: Brand vs. generic · U.S. prices · Insurance · Medicare · Maker savings · Who makes it · Brand or generic · Uses · FAQ

Generic Dificid: fidaxomicin 200 mg tablets, usually one 10-day course of 20 tablets. Who makes it and U.S. cash prices. Also sold as: Dificid (brand, Merck), Dificlir (brand name in the U.K. and Europe)

Fidaxomicin names

- Brand name: Dificid (Merck)
- Generic name: fidaxomicin
- Names in Canada: Dificid (Health Canada Drug Product Database, marketed products, checked Oct 29, 2026)
- Other names: Dificlir (brand name in the U.K. and Europe)

Fidaxomicin packs made for other countries are not FDA-approved.

Who makes generic fidaxomicin in the U.S.

FDA drug listings show FDA-approved generic fidaxomicin from Apotex, Hikma, Sandoz, Teva and Torrent (FDA NDC Directory, checked Oct 29, 2026).

StrengthU.S. genericMakersSince
200 mgYesTeva (Actavis), Torrent, Apotex, Sandoz, HikmaJul 15, 2025

Outside the U.S.: We found no generic fidaxomicin at the licensed pharmacies abroad we compared. In the U.K. and Europe the brand is sold as Dificlir.

Source: FDA Orange Book: fidaxomicin products. As of Oct 29, 2026.

Fidaxomicin FAQ

How much does generic Dificid cost without insurance?

In our latest check, a 10-day course of generic fidaxomicin 200 mg (20 tablets) cost from $1,416.84 at the U.S. pharmacy that posts a cash price, shipping included. For comparison, U.S. list prices for 20 tablets are $4,497.12 for Teva's generic and $5,205 for brand Dificid (the makers' 2026 prices before discounts, as reported to the Texas Department of State Health Services). Prices change often, so check before you buy.

Is fidaxomicin the same as Dificid?

Fidaxomicin is the active ingredient in Dificid, and the generic name. FDA-approved generic fidaxomicin tablets are rated AB, which means the FDA considers them equivalent to Dificid.

Is there a generic Dificid liquid?

No. The FDA Orange Book lists no generic of Dificid oral suspension. Generics are sold only as 200 mg tablets.

Does Medicare cover fidaxomicin?

It depends on your Part D plan's drug list, which you can search with Medicare's Plan Finder. In 2026, Part D deductibles are up to $615 and out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027).

Who makes generic Dificid in the U.S.?

The FDA Orange Book lists generic fidaxomicin 200 mg tablets from Teva (Actavis), Torrent, Apotex, Sandoz and Hikma.

When did generic Dificid come out?

Teva's generic fidaxomicin has been listed for sale in the U.S. since July 15, 2025. Torrent, Apotex, Sandoz and Hikma followed between January and October 2026.

Can I buy generic Dificid from pharmacies abroad?

We found only brand Dificid and Dificlir at the licensed pharmacies abroad we compared, no generic. Their prices are on the Dificid page.

Brand vs. generic: cost for one 10-day course

Option90 days
Generic fidaxomicin 200 mg, U.S. pharmacy cash priceLowest U.S. pharmacy price we found, checked Oct 29, 2026$1,416.84
Brand Dificid 200 mg from licensed pharmacies abroadLowest price we found, shipping included, checked Nov 11, 2026$2,808.95
Brand Dificid, U.S. list priceBefore insurance; pharmacies may charge more$5,205

Lowest in this comparison: Generic fidaxomicin 200 mg, U.S. pharmacy cash price.

90 days = 20 tablets of 200 mg. Generic sold abroad is not FDA-approved and is not in this box. Your price with insurance or Medicare depends on your plan.

See brand Dificid prices

Generic fidaxomicin price in the U.S.

U.S. pharmacyStrengthPackPrice90 daysChecked
Lowest U.S. pharmacy cash price we found (members see the pharmacy in the price table)20 tablets (one 10-day course) plus standard shipping200 mg20 tablets$1,411.59$1,416.84Oct 29, 2026

These are cash prices U.S. pharmacies post on their own websites, before insurance. The price table at the top of the page lists every U.S. price we found, by strength. Your local pharmacy can tell you its own price, and it may be different.

Cash prices each pharmacy published on its own website on the date shown, before insurance. 90 days = one order of whole packs (as close to 90 days as the pack sizes allow, never over 92), worked out to 90 days at the usual dose so pack sizes compare fairly. We don't list coupon or discount-card prices. Prices change; confirm with the pharmacy.

Fidaxomicin cost at a glance

  • FDA-approved generics are sold in the U.S. The FDA approved generic fidaxomicin 200 mg tablets from Teva, Torrent, Apotex, Sandoz and Hikma, all rated equivalent to Dificid. Teva's has been listed for sale since July 15, 2025.
  • U.S. cash price: $1,416.84 for one 10-day course (20 tablets) of fidaxomicin 200 mg at the lowest U.S. pharmacy we found, shipping included.
  • U.S. list prices: Teva's generic fidaxomicin is $4,497.12 for 20 tablets, and brand Dificid is $5,205 (the makers' 2026 prices before discounts). List prices are what pharmacies pay, not what you pay.
  • Abroad: we found only brand Dificid (and Dificlir) at licensed pharmacies abroad, no generic. See the brand page for those prices.
  • One course, not a monthly refill: the label's usual adult dose is one 200 mg tablet twice a day for 10 days, so prices are for 20 tablets.

How much does Fidaxomicin cost in the U.S.?

If you haveWhat Fidaxomicin costsSource
No insurance (U.S. cash price)Generic fidaxomicin 200 mg from $1,416.84 for one 10-day course (20 tablets) at the lowest U.S. pharmacy we found, shipping included. Prices vary by pharmacy.Price table above
No insurance (U.S. list price)Teva's generic fidaxomicin: $4,497.12 for 20 tablets. Brand Dificid: $5,205 for 20 tablets. These are the makers' 2026 U.S. list prices before discounts; other makers' prices may differ.Texas DSHS 2026 WAC report
Private or employer insuranceYour copay depends on your plan's drug list, tier and deductible.Your plan
Medicare Part DCoverage and copay depend on your plan. Check which plans cover fidaxomicin with Medicare's Plan Finder.Medicare.gov
MedicaidYour state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office.Medicaid.gov

Cash prices are what you pay without insurance, from the pharmacies' own websites. Brand list prices are wholesale prices, not what you pay; pharmacies may charge more or less.

Fidaxomicin cost with Medicare in 2026

Each Part D plan has its own list of covered drugs and copays, so what you pay for fidaxomicin depends on your plan (Medicare Plan Finder). In 2026, Part D plans can have a yearly deductible of up to $615, and your out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027) (Medicare.gov). Merck's patient assistance program is for brand Dificid, and Medicare counts as coverage under its rules.

Medicare Part DWhat Fidaxomicin costsSource
Part D deductible (2026)Up to $615 a year, depending on your planMedicare.gov
Yearly out-of-pocket cap (2026)$2,100 for covered Part D drugs ($2,400 in 2027)Medicare.gov
Which plans cover fidaxomicinSearch your plan's drug list with your ZIP codeMedicare Plan Finder

Savings programs from the maker

How do you pay?

We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.

eDrugSearch does not offer its own Fidaxomicin coupons. Merck's Patient Assistance Program is for brand Dificid only (see the brand page). These programs can lower what you pay for generic fidaxomicin:

  • Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
  • Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
  • Costco Pharmacy member prices: Costco publishes member prices for many prescriptions, for people with a Costco membership. Non-members can also use Costco pharmacies and pay the regular cash price. Member prices can't be used with insurance, Medicare or Medicaid claims. (Costco Pharmacy)
  • Amazon Pharmacy Prime and RxPass: Amazon Pharmacy offers Prime members discounts on many prescriptions, and RxPass, for Prime members, covers a set list of generics for a flat monthly fee. Prime is not required to use Amazon Pharmacy. Prime savings have limits for people with Medicare, Medicaid or Tricare, and RxPass is not open to people with Medicaid or CHIP. (Amazon Pharmacy)
  • Discount cards: Discount cards (for example GoodRx or SingleCare) may lower the price at local pharmacies; prices vary by pharmacy and ZIP code.

When people choose brand Dificid

Some people get brand Dificid instead of generic fidaxomicin. Common reasons:

  • A prescription marked “dispense as written” (or “brand medically necessary”) tells the pharmacy to fill brand Dificid, not a generic. State laws set the rules for generic substitution.
  • Merck gives free brand Dificid to eligible U.S. residents with no prescription coverage and household income within its limits (Merck Helps). Call 1-800-727-5400 to check.
  • Some insurance and Medicare drug plans cover the brand and the generic at different copays, or cover only one of them. Your plan's drug list shows which.

Your prescriber decides which medicine is right for you.

Compare prices for your other medicines

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength.

What is Fidaxomicin used for?

Fidaxomicin is a macrolide antibiotic, the same medicine as in Dificid. According to the Dificid FDA label (prescribing information), it is used:

  • To treat diarrhea caused by Clostridioides difficile (C. diff) in adults and children 6 months and older.

The label's usual adult dose is one 200 mg tablet twice a day for 10 days (20 tablets). The label says it should be used only for infections proven or strongly suspected to be caused by C. diff, because it is not expected to work for other infections. It has no boxed warning. Check the label that comes with your medicine. Your prescriber decides which medicine is right for you.

Is it safe to order Fidaxomicin from Canada?

Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress declared in FD&C Act 804(j)(1), 21 U.S.C. 384(j)(1), that enforcement against individuals should focus on imports posing a significant threat to public health. You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. We found no generic fidaxomicin at licensed pharmacies abroad, and FDA-approved generics are sold in the U.S.

Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.

Sources

eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.