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Linzess Price (linaclotide)

As of Nov 11, 2026, brand Linzess 145 mcg costs from $414.95 for 90 days at licensed pharmacies abroad (ships from Canada; packs made for other countries are not FDA-approved), vs. $847.44 at the U.S. list price.

Lowest U.S. online pharmacy price
$10.04 per capsule$908.60 for 90 days (90 capsules), shipping included · FDA-approved brand Linzess 145 mcg · ships within the U.S.
Lowest international online pharmacy price
$4.29 per capsule$386.05 for 90 days (90 capsules), plus shipping (fee not published) · brand Linzess 145 mcg, not FDA-approved · ships from Canada
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Prices checked Nov 11, 2026 · Page updated November 11, 2026 · By the eDrugSearch team · How we check pharmacies and prices

Compare Linzess prices from licensed pharmacies

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For comparison U.S. pharmacy list price: $847.44 for 90 days ($9.42 per capsule), brand Linzess 72 mcg, 145 mcg or 290 mcg before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.

PharmacyMedicationPriceShipping & deliveryTotal (90 days)Buy
Online pharmacy AConstella 290mcg290 mcg · brand · Filled in United KingdomMaker listed by pharmacy: AbbVie Ltd$281.40for 84 capsules$3.35 per capsule$14.95Pharmacy's estimate: 4–6 weeks$296.35 for 84 days= $317.52 for 90 daysSave 63%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy BCONSTELLA290 mcg · brand · Filled in UKProduct of UK$326.56for 84 capsules$3.89 per capsuleFreeDelivery time not stated$326.56 for 84 days= $349.89 for 90 daysSave 59%Worked out from an 84-day orderChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy CConstella 290mcg Capsule (UK/EU pack, ships from United Kingdom)290 mcg · brand · Filled in United KingdomMaker listed by pharmacy: Maker not shown by pharmacyMade for UK/EU$336.12for 84 capsules$4.00 per capsuleFee not publishedDelivery time not stated$336.12 for 84 days= $360.13 for 90 days+ shippingSave 58%Worked out from an 84-day orderChecked Nov 7See pharmacy (members) Members see the pharmacy
Online pharmacy DConstella (UK/EU pack, ships from United Kingdom)290 mcg · brand · Filled in United KingdomProduct of UK/EU$345.99for 84 capsules$4.12 per capsuleFee not publishedDelivery time not stated$345.99 for 84 days= $370.70 for 90 days+ shippingSave 56%Worked out from an 84-day orderChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy CConstella 72mcg Capsule72 mcg · brand · Filled in CanadaMaker listed by pharmacy: Maker not shown by pharmacy$373.68for 90 capsules$4.15 per capsuleFee not publishedDelivery time not stated$373.68 for 90 days= $373.68 for 90 days+ shippingSave 56%incl. $0 shippingChecked Nov 7See pharmacy (members) Members see the pharmacy
Online pharmacy BLINZESS290 mcg · brand · Filled in UKProduct of UK$357.37for 84 capsules$4.25 per capsuleFreeDelivery time not stated$357.37 for 84 days= $382.90 for 90 daysSave 55%Worked out from an 84-day orderChecked Nov 11See pharmacy (members) Members see the pharmacy
Licensed online pharmacy ELinzess 290mcg290 mcg · brand · Filled in United KingdomProduct of United Kingdom$358for 84 capsules$4.26 per capsuleFreeDelivery time not stated$358 for 84 days= $383.57 for 90 daysSave 55%Worked out from an 84-day orderChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy FLinzess 72mcg (United States pack, ships from Canada)72 mcg · brand · Filled in CanadaMaker listed by pharmacy: Allergan Inc.Made for United States$375for 90 capsules$4.17 per capsule$9.95Pharmacy's estimate: 4–6 weeks$384.95 for 90 days= $384.95 for 90 daysSave 55%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy DConstella72 mcg · brand · Filled in CanadaProduct of Canada$384.99for 90 capsules$4.28 per capsuleFee not publishedDelivery time not stated$384.99 for 90 days= $384.99 for 90 days+ shippingSave 55%incl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy CConstella 145mcg Capsule145 mcg · brand · Filled in CanadaMaker listed by pharmacy: Maker not shown by pharmacy$386.05for 90 capsules$4.29 per capsuleFee not publishedDelivery time not stated$386.05 for 90 days= $386.05 for 90 days+ shippingSave 54%incl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy DConstella145 mcg · brand · Filled in CanadaProduct of Canada$396.99for 90 capsules$4.41 per capsuleFee not publishedDelivery time not stated$396.99 for 90 days= $396.99 for 90 days+ shippingSave 53%incl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy GConstella 290mcg Capsule290 mcg · brand · Filled in United KingdomMaker listed by pharmacy: Abbvie Corp.$379.49for 84 capsules$4.52 per capsuleFreePharmacy's estimate: 2–3 weeks$379.49 for 84 days= $406.60 for 90 daysSave 52%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy FLinzess 145mcg Capsule (United States pack, ships from Canada)145 mcg · brand · Filled in CanadaMaker listed by pharmacy: Allergan Inc.Made for United States$405for 90 capsules$4.50 per capsule$9.95Pharmacy's estimate: 4–6 weeks$414.95 for 90 days= $414.95 for 90 daysSave 51%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy AConstella 145mcg145 mcg · brand · Filled in CanadaMaker listed by pharmacy: AbbVie Ltd$400.50for 90 capsules$4.45 per capsule$14.95Pharmacy's estimate: 4–6 weeks$415.45 for 90 days= $415.45 for 90 daysSave 51%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy HConstella72 mcg · brand · Filled in CanadaMaker listed by pharmacy: ABBVIE CORPORATION$422.23for 90 capsules$4.69 per capsule$9.95Pharmacy's estimate: 3–6 weeks$432.18 for 90 days= $432.18 for 90 daysSave 49%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy AConstella 72mcg72 mcg · brand · Filled in CanadaMaker listed by pharmacy: AbbVie Ltd$432for 90 capsules$4.80 per capsule$14.95Pharmacy's estimate: 4–6 weeks$446.95 for 90 days= $446.95 for 90 daysSave 47%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy HConstella145 mcg · brand · Filled in CanadaMaker listed by pharmacy: ABBVIE CORPORATION$438.77for 90 capsules$4.88 per capsule$9.95Pharmacy's estimate: 3–6 weeks$448.72 for 90 days= $448.72 for 90 daysSave 47%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy IConstella (Canadian name for Linzess)145 mcg · brand · Filled in CanadaMaker listed by pharmacy: Abbvie Corp.$145.50per 30 capsules · 3 packs = $436.50$4.85 per capsule$14.99Delivery time not stated$451.49 for 90 days= $451.49 for 90 daysSave 47%incl. $14.99 shippingChecked Oct 25See pharmacy (members) Members see the pharmacy
Online pharmacy GConstella 145mcg Capsule145 mcg · brand · Filled in CanadaMaker listed by pharmacy: Abbvie Corp.$455.19for 90 capsules$5.06 per capsuleFreePharmacy's estimate: 2–3 weeks$455.19 for 90 days= $455.19 for 90 daysSave 46%incl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy JLinzess (Linaclotide)72 mcg · brand · Filled in CanadaProduct of Canada$449.94for 90 capsules$5.00 per capsule$14.99Delivery time not stated$464.93 for 90 days= $464.93 for 90 daysSave 45%incl. $14.99 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy JLinzess (Linaclotide)145 mcg · brand · Filled in CanadaProduct of Canada$449.94for 90 capsules$5.00 per capsule$14.99Delivery time not stated$464.93 for 90 days= $464.93 for 90 daysSave 45%incl. $14.99 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy KBrand Constella 145mcg145 mcg · brand · Filled in CanadaMaker listed by pharmacy: ALLERGAN$460.05for 90 capsules$5.11 per capsule$14.95Pharmacy's estimate: 4–6 weeks$475 for 90 days= $475 for 90 daysSave 44%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy FLinzess 290mcg290 mcg · brand · Filled in United KingdomMaker listed by pharmacy: Allergan Inc.$435for 84 capsules$5.18 per capsule$9.95Pharmacy's estimate: 4–6 weeks$444.95 for 84 days= $476.73 for 90 daysSave 44%Worked out from an 84-day orderChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy ELinzess 145mcg145 mcg · brand · Filled in CanadaProduct of Canada$490for 90 capsules$5.44 per capsuleFreeDelivery time not stated$490 for 90 days= $490 for 90 daysSave 42%incl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy IConstella (Canadian name for Linzess)72 mcg · brand · Filled in CanadaMaker listed by pharmacy: Abbvie Corp.$164.50per 30 capsules · 3 packs = $493.50$5.48 per capsule$14.99Delivery time not stated$508.49 for 90 days= $508.49 for 90 daysSave 40%incl. $14.99 shippingChecked Oct 25See pharmacy (members) Members see the pharmacy
Online pharmacy GConstella 72mcg Capsule72 mcg · brand · Filled in CanadaMaker listed by pharmacy: Abbvie Corp.$518.19for 90 capsules$5.76 per capsuleFreePharmacy's estimate: 2–3 weeks$518.19 for 90 days= $518.19 for 90 daysSave 39%incl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy LBrand Constella 145mcg145 mcg · brand · Filled in CanadaMaker listed by pharmacy: ALLERGAN$504.06for 90 capsules$5.60 per capsule$14.95Pharmacy's estimate: 4–6 weeks$519.01 for 90 days= $519.01 for 90 daysSave 39%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy KBrand Constella 72mcg72 mcg · brand · Filled in CanadaMaker listed by pharmacy: ALLERGAN$518.73for 90 capsules$5.76 per capsule$14.95Pharmacy's estimate: 4–6 weeks$533.68 for 90 days= $533.68 for 90 daysSave 37%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy MBrand Constella 145mcg145 mcg · brand · Filled in CanadaMaker listed by pharmacy: ALLERGAN$529.26for 90 capsules$5.88 per capsule$14.95Pharmacy's estimate: 4–6 weeks$544.21 for 90 days= $544.21 for 90 daysSave 36%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy LBrand Constella 72mcg72 mcg · brand · Filled in CanadaMaker listed by pharmacy: ALLERGAN$568.60for 90 capsules$6.32 per capsule$14.95Pharmacy's estimate: 4–6 weeks$583.55 for 90 days= $583.55 for 90 daysSave 31%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy FLinzess 290mcg Capsule (United States pack, ships from Canada)290 mcg · brand · Filled in CanadaMaker listed by pharmacy: Allergan Inc.Made for United States$585for 90 capsules$6.50 per capsule$9.95Pharmacy's estimate: 4–6 weeks$594.95 for 90 days= $594.95 for 90 daysSave 30%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy BLINZESS145 mcg · brand · Filled in CanadaProduct of Canada$606.71for 90 capsules$6.74 per capsuleFreeDelivery time not stated$606.71 for 90 days= $606.71 for 90 daysSave 28%incl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy BLINZESS (EU pack, ships from Canada)72 mcg · brand · Filled in CanadaProduct of EU$606.71for 90 capsules$6.74 per capsuleFreeDelivery time not stated$606.71 for 90 days= $606.71 for 90 daysSave 28%incl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy MBrand Constella 72mcg72 mcg · brand · Filled in CanadaMaker listed by pharmacy: ALLERGAN$597.03for 90 capsules$6.63 per capsule$14.95Pharmacy's estimate: 4–6 weeks$611.98 for 90 days= $611.98 for 90 daysSave 28%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy Elinzess 145mcg145 mcg · brand · Filled in CanadaProduct of Canada$208per 30 capsules · 3 packs = $624$6.93 per capsuleFreeDelivery time not stated$624 for 90 days= $624 for 90 daysSave 26%incl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy HConstella290 mcg · brand · Filled in CanadaMaker listed by pharmacy: ABBVIE CORPORATION$620.68for 90 capsules$6.90 per capsule$9.95Pharmacy's estimate: 3–6 weeks$630.63 for 90 days= $630.63 for 90 daysSave 26%incl. $9.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy AConstella 290mcg290 mcg · brand · Filled in CanadaMaker listed by pharmacy: AbbVie Ltd$639for 90 capsules$7.10 per capsule$14.95Pharmacy's estimate: 4–6 weeks$653.95 for 90 days= $653.95 for 90 daysSave 23%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy BCONSTELLA (EU pack, ships from Canada)145 mcg · brand · Filled in CanadaProduct of EU$223.32per 30 capsules · 3 packs = $669.96$7.44 per capsuleFreeDelivery time not stated$669.96 for 90 days= $669.96 for 90 daysSave 21%incl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy BCONSTELLA (EU pack, ships from Canada)72 mcg · brand · Filled in CanadaProduct of EU$223.32per 30 capsules · 3 packs = $669.96$7.44 per capsuleFreeDelivery time not stated$669.96 for 90 days= $669.96 for 90 daysSave 21%incl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy KBrand Constella 290mcg290 mcg · brand · Filled in CanadaMaker listed by pharmacy: ALLERGAN$684.66for 90 capsules$7.61 per capsule$14.95Pharmacy's estimate: 4–6 weeks$699.61 for 90 days= $699.61 for 90 daysSave 17%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy ELinzess 290mcg290 mcg · brand · Filled in CanadaProduct of Canada$736for 90 capsules$8.18 per capsuleFreeDelivery time not stated$736 for 90 days= $736 for 90 daysSave 13%incl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Licensed Canadian pharmacy JLinzess (Linaclotide)290 mcg · brand · Filled in CanadaProduct of Canada$749.94for 90 capsules$8.33 per capsule$14.99Delivery time not stated$764.93 for 90 days= $764.93 for 90 daysSave 10%incl. $14.99 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy LBrand Constella 290mcg290 mcg · brand · Filled in CanadaMaker listed by pharmacy: ALLERGAN$751.13for 90 capsules$8.35 per capsule$14.95Pharmacy's estimate: 4–6 weeks$766.08 for 90 days= $766.08 for 90 daysSave 10%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy MBrand Constella 290mcg290 mcg · brand · Filled in CanadaMaker listed by pharmacy: ALLERGAN$788.69for 90 capsules$8.76 per capsule$14.95Pharmacy's estimate: 4–6 weeks$803.64 for 90 days= $803.64 for 90 daysSave 5%incl. $14.95 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy IConstella (Canadian name for Linzess)290 mcg · brand · Filled in CanadaMaker listed by pharmacy: Abbvie Corp.$265.50per 30 capsules · 3 packs = $796.50$8.85 per capsule$14.99Delivery time not stated$811.49 for 90 days= $811.49 for 90 daysSave 4%incl. $14.99 shippingChecked Oct 25See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy NLinzess 72mcg Caps 30 Count Bottle72 mcg · brandMaker listed by pharmacy: Allergan, Inc.Ships from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026$285.63per 30 capsules · 3 packs = $856.89$9.52 per capsule$5Pharmacy's estimate: 2–8 business days$861.89 for 90 days= $861.89 for 90 daysincl. $5 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy GConstella 290mcg Capsule290 mcg · brand · Filled in CanadaMaker listed by pharmacy: Abbvie Corp.$902.58for 90 capsules$10.03 per capsuleFreePharmacy's estimate: 2–3 weeks$902.58 for 90 days= $902.58 for 90 daysincl. $0 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy NLinzess 145mcg Caps 30 Count Bottle145 mcg · brandMaker listed by pharmacy: Allergan, Inc.Ships from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026$903.60for 90 capsules$10.04 per capsule$5Pharmacy's estimate: 2–8 business days$908.60 for 90 days= $908.60 for 90 daysincl. $5 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Licensed U.S. pharmacy NLinzess 290mcg Caps 30 Count Bottle290 mcg · brandMaker listed by pharmacy: Allergan, Inc.Ships from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026$903.60for 90 capsules$10.04 per capsule$5Pharmacy's estimate: 2–8 business days$908.60 for 90 days= $908.60 for 90 daysincl. $5 shippingChecked Nov 5See pharmacy (members) Members see the pharmacy
Online pharmacy BLINZESS290 mcg · brand · Filled in CanadaProduct of Canada$946.99for 90 capsules$10.52 per capsuleFreeDelivery time not stated$946.99 for 90 days= $946.99 for 90 daysincl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy
Online pharmacy BCONSTELLA (EU pack, ships from Canada)290 mcg · brand · Filled in CanadaProduct of EU$337.61per 30 capsules · 3 packs = $1,012.83$11.25 per capsuleFreeDelivery time not stated$1,012.83 for 90 days= $1,012.83 for 90 daysincl. $0 shippingChecked Nov 11See pharmacy (members) Members see the pharmacy

Buying from a pharmacy outside the U.S.? Read Is it safe to order Linzess from Canada?

90-day cost = 90 capsules at the usual dose of 1 a day, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 11, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price of the same strength (72 mcg, 145 mcg or 290 mcg). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.

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90-day prices from 11 licensed pharmacies abroad shipping to the U.S.: $317.52 to $1,012.83, any strength, shipping included.

Jump to: Medicare · Maker savings · Generic Linzess · Similar drugs · Uses · FAQ

Linzess (linaclotide) 72, 145 and 290 mcg capsules for IBS with constipation and chronic constipation. No generic is on sale in the U.S. yet. Also sold as: Constella (Canada and U.K.)

Linzess price by strength

StrengthLowest brand90 daysPrice per capsule
Linzess 72 mcg$384.95$4.17
Linzess 145 mcg$414.95$4.50
Linzess 290 mcg$317.52$3.35

Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per capsule is for that lowest pack, before shipping. Prices checked Nov 11, 2026.

Cheapest ways to get Linzess 145 mcg

The cheapest ways we found to get brand Linzess 145 mcg (prices checked Nov 11, 2026). The lowest 90-day cost is shaded green.

Way to buyCostDetails
Licensed online pharmacy abroad$414.95 for 90 daysBrand Linzess 145 mcg, ships from Canada, not FDA-approved (made for another country). Shipping included, checked Nov 11, 2026. See all prices
U.S. pharmacy cash price$908.60 for 90 daysFDA-approved brand Linzess 145 mcg, ships within the U.S. (no customs). Shipping included, checked Nov 5, 2026. See all prices
U.S. list price$847.44 for 90 daysBrand Linzess before insurance. Pharmacies may charge more.
Maker’s patient assistance programMay be free if you qualifymyAbbVie Assist, checked Oct 29, 2026. Who qualifies
Medicare (negotiated price)$136 per 30 days starting January 1, 2027What Medicare will pay starting January 1, 2027, not your copay. In 2026 your cost depends on your Part D plan. CMS · Medicare costs

Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.

How much does Linzess cost without insurance?

Without insurance, Linzess costs $282.48 for a 30-day supply at the U.S. list price, or about $847.44 for 90 days. Licensed pharmacies abroad charged from $414.95 for 90 days of brand Linzess 145 mcg in our latest check (Nov 11, 2026), shipping included. Cash: The copay program is not valid for cash-paying patients. We found no maker cash price and no TrumpRx.gov listing (checked October 24, 2026). AbbVie's patient assistance program may help if you qualify. (AbbVie (LINZESS.com)) myAbbVie Assist (AbbVie patient assistance): AbbVie's patient assistance program provides AbbVie medicine to qualifying patients. The Linzess site points people without insurance, or who have trouble paying, to this program. Call myAbbVie Assist at 1-800-222-6885 to ask if you qualify, or the Linzess help line at 1-855-226-3937 (myAbbVie Assist).

Linzess cost with Medicare

In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Linzess depends on your plan's drug list and your coverage phase. Starting January 1, 2027, Medicare will pay a negotiated price of $136 for a 30-day supply of Linzess (CMS, checked Oct 30, 2026). That's what Medicare will pay, not your copay. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.

Medicare Part DWhat Linzess costsSource
Part D deductible (2026)Up to $615 a year, depending on your planMedicare.gov
Yearly out-of-pocket cap (2026)$2,100 for covered Part D drugs ($2,400 in 2027)Medicare.gov
Medicare negotiated price$136 for a 30-day supply, starting January 1, 2027CMS

Linzess cost with insurance

With private or employer insurance, what you pay for Linzess depends on your plan's drug list, deductible and copay. As little as $30 for a 30-, 60- or 90-day supply with the Linzess Savings Program, up to 12 fills and $2,280 in savings a year (AbbVie (LINZESS.com)).

Medicaid: Depends on your state plan. The copay program can't be used with Medicaid (AbbVie (LINZESS.com)).

Linzess patient assistance program

Yes. Linzess is offered through myAbbVie Assist, which can give the medicine at no cost to people who qualify. Who qualifies: People in the U.S. with limited or no health insurance coverage who meet income limits: household income of $77,280 or less for 1 person, $104,520 for 2, $131,760 for 3 or $159,000 for 4 (add $27,240 for each extra person). People with insurance may also be reviewed based on their coverage. How to apply: Apply for free through AbbVie (online or with the paper application for your medicine), or call 1-800-222-6885 with questions. (Checked 2026-10-29.)

Is there a generic Linzess?

No. No generic Linzess is on sale in the U.S. FDA records list approved generic linaclotide, but none is sold. Under settlements, Teva may start selling generic linaclotide on March 31, 2029, or earlier in limited cases.

StrengthU.S. genericMakersSince
72 mcgNo—
145 mcgNo—
290 mcgNo—

Outside the U.S.: Sold as Constella (AbbVie) in Canada and the U.K. We found no generic linaclotide abroad that we could confirm.

Source: FDA Drugs@FDA: linaclotide applications. As of Oct 25, 2026.

Linzess FAQ

How much does Linzess cost without insurance?

As of Nov 11, 2026, licensed pharmacies abroad we compared sold 90 days of brand Linzess 145 mcg from $414.95, shipping included. The U.S. list price is $282.48 for 30 capsules of any strength ($847.44 for 90 days), as of January 2026. The maker's copay program can't be used by cash-paying patients, but AbbVie's patient assistance program may help if you qualify.

How much does Linzess cost with Medicare?

It depends on your Part D plan. In 2026, Part D out-of-pocket costs are capped at $2,100 a year ($2,400 in 2027). Starting January 1, 2027, Medicare will pay a negotiated price of $136 for a 30-day supply of Linzess. People with limited income can apply for Extra Help to lower their costs.

How much does Linzess 290 mcg cost?

The U.S. list price is the same for every strength: $282.48 for 30 capsules. Online pharmacies abroad charged $317.52 to $1,012.83 for 90 days of brand 290 mcg in our latest check (Nov 11, 2026), shipping included.

Is there a generic Linzess?

Not on sale in the U.S. yet. The FDA has approved some generic linaclotide, but none is sold. Under a settlement, Teva may start selling generic linaclotide on March 31, 2029, or earlier in limited cases.

Why is Linzess so expensive?

No generic Linzess is on sale in the U.S. yet, so only the brand is sold. The maker cut the U.S. list price to $282.48 a month on January 1, 2026.

Is Constella the same as Linzess?

Yes. Constella is the name AbbVie uses for linaclotide in Canada and the U.K. It is the same medicine. Canada sells 72 mcg, 145 mcg and 290 mcg capsules; the U.K. product we found is 290 mcg.

How can I get Linzess for $30?

With the Linzess Savings Program, eligible patients with private or employer insurance may pay as little as $30 for a 30-, 60- or 90-day supply, with up to $2,280 in savings a year. It can't be used with Medicare, Medicaid or other government insurance, or if you pay cash.

Savings programs from the maker

eDrugSearch does not offer its own Linzess coupons. These are the real savings programs, run by the drug's maker and by Medicare:

  • Linzess Savings Program: for people with private or employer insurance. Eligible patients may pay as little as $30 for a 30-, 60- or 90-day supply, for up to 12 fills a year, with up to $2,280 in savings a year. Not for Medicare, Medicaid or other government programs, and not for cash-paying patients. Sign up at 1-855-859-5614 or text LINZESS to 59257. (Linzess savings card terms)
  • myAbbVie Assist: AbbVie's patient assistance program provides AbbVie medicine to qualifying patients. Call myAbbVie Assist at 1-800-222-6885, or the Linzess help line at 1-855-226-3937. (AbbVie patient assistance)
  • Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
  • Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)

Compare Linzess with similar drugs

Other medicines people often compare with Linzess for chronic constipation or IBS-C, including Trulance, which works in a similar way. Prices are for each drug's lowest-priced strength.

DrugTypeLowest price we foundLink
TrulanceplecanatideConstipation and IBS-C medicine (guanylate cyclase-C agonist)$734.99 for 90 daysSee prices
IbsrelatenapanorIBS-C medicine (NHE3 inhibitor)Checking pricesSee prices
MotegrityprucaloprideChronic constipation medicine (serotonin-4 receptor agonist)$81.85 for 90 daysSee prices

Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.

What is Linzess used for?

Linzess (linaclotide) is a guanylate cyclase-C agonist. According to its FDA label (DailyMed), it is used to treat:

  • Irritable bowel syndrome with constipation (IBS-C) in adults and children 7 years and older.
  • Chronic idiopathic constipation (CIC) in adults.
  • Functional constipation in children 2 years and older.

Linzess comes as 72 mcg, 145 mcg and 290 mcg capsules. Its label has a boxed warning: it must not be used in children under 2 because of the risk of serious dehydration. Your prescriber decides which medicine is right for you.

Is it safe to order Linzess from Canada?

Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply. Congress declared in FD&C Act 804(j)(1), 21 U.S.C. 384(j)(1), that enforcement against individuals should focus on imports posing a significant threat to public health. You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada and the U.K., Linzess is sold as Constella, made by AbbVie. If you have private insurance, the maker's savings card may cost less than ordering from abroad.

Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.

Sources

eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.