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Enstilar Price, Coupons and Savings
- U.S. list price
- $22.79 per gThe maker's price for brand Enstilar before discounts · Source: Texas DSHS
- Lowest price per g at online pharmacies abroad
- $2.21 per gIn a pack of 180 g for $398.49 (before shipping) · brand Enstilar 50 mcg/g + 0.5 mg/g, not FDA-approved · ships from Canada
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Quick answerAs of Nov 2, 2026, brand Enstilar foam costs from $2.21 per g at licensed pharmacies abroad we compared, before shipping, vs. about $22.79 a gram at the U.S. list price ($1,367.13 for a 60 g can). With commercial insurance, LEO's copay card can lower the cost to as little as $30.
Name check: Taclonex (ointment, suspension) and Wynzora (cream) have the same two ingredients but are different products, so their prices are not mixed in here.
Compare Enstilar prices from licensed online pharmacies
For comparison U.S. pharmacy list price: $22.79 per g, brand Enstilar before insurance. The prices below are from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Pack | Price per unit | Pack price | Shipping & delivery | Total with shipping | Buy |
|---|---|---|---|---|---|---|---|
| Lowest price per unitOnline pharmacy A | Enstilar Aerosol Foam 50mcg/g 0.5mg/g Aerosol, Foam50 mcg/g + 0.5 mg/g · brand · Filled in CanadaMaker listed by pharmacy: Maker not shown by pharmacy | 60 g | $1.88 per g | $112.69 | Fee not publishedDelivery time not stated | $112.69+ shippingChecked Nov 7 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy B | Enstilar Aerosol Foam 50mcg/g 0.5mg/g Aerosol, Foam50 mcg/g + 0.5 mg/g · brand · Filled in CanadaMaker listed by pharmacy: Leo Pharma Inc. | 180 g2 other pack sizes
| $2.21 per g | $398.49 | FreePharmacy's estimate: 2–3 weeks | $398.49Checked Nov 7 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitOnline pharmacy C | Enstilar Aerosol Foam 50mcg/g 0.5mg/g50 mcg/g + 0.5 mg/g · brand · Filled in CanadaMaker listed by pharmacy: Leo Pharma Inc. | 180 g2 other pack sizes
| $2.42 per g | $435 | $9.95Pharmacy's estimate: 4–6 weeks | $444.95Checked Nov 7 | See pharmacy (members) Members see the pharmacy |
| Lowest price per unitLicensed Canadian pharmacy D | Enstilar Aerosol Foam 50mcg/g 0.5mg/g50 mcg/g + 0.5 mg/g · brand · Filled in CanadaMaker listed by pharmacy: Leo Pharma | 180 g2 other pack sizes
| $2.55 per g | $458.61 | $9.95Pharmacy's estimate: 3–6 weeks | $468.56Checked Nov 2 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Enstilar from Canada?
Each row is one product from one pharmacy, shown in the pack size with the lowest price per unit; its other pack sizes are listed under “other pack sizes”. Price per unit = the pack price divided by the units in the pack, before shipping; we sort by it and don't assume how long a pack lasts. Total with shipping = the pack price plus the pharmacy's shipping fee for one order. Prices checked Nov 2, 2026 on each pharmacy's website, in U.S. dollars (converted when a pharmacy prices in Canadian dollars). The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Prices change often; confirm at checkout. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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Prices per g from 3 licensed pharmacies shipping to the U.S.: $2.21 to $2.55, any strength, before shipping.
Jump to: U.S. cost · Medicare · Coupons & savings · Generic Enstilar · Similar drugs · Uses · FAQ
Enstilar (calcipotriene and betamethasone dipropionate) foam for plaque psoriasis, in 60 g cans. No generic Enstilar foam is sold in the U.S.
Enstilar cost at a glance
- No generic Enstilar foam is sold in the U.S. The FDA approved one generic foam (Glenmark, 2023), but FDA records list it as discontinued, and no generic foam is in the FDA's drug listing. Generic ointment and suspension with the same ingredients are sold, but they're different products.
- U.S. list price: $1,367.13 for one 60 g can and $2,734.24 for a pack of two cans, as LEO Pharma reported to Texas for 2026. Pharmacies may charge more.
- With private or employer insurance: eligible patients may pay as little as $30 per prescription with the LEO Pharma CONNECT co-pay card, with savings up to $6,000 a year.
- With Medicare: the copay card can't be used. Your cost depends on your Part D plan, and out-of-pocket costs for covered drugs are capped at $2,100 in 2026.
- From online pharmacies abroad: $2.21 to $2.55 per g for brand Enstilar, before shipping (checked Nov 2, 2026). We compare prices per gram; your prescriber decides how much you use.
How much does Enstilar cost in the U.S.?
| If you have | What Enstilar costs | Source |
|---|---|---|
| No insurance (list price) | $1,367.13 for one 60 g can; $2,734.24 for two 60 g cans (LEO Pharma's 2026 list-price report to Texas). Pharmacies may charge more. | Texas DSHS |
| Private or employer insurance | As little as $30 per prescription with the LEO Pharma CONNECT co-pay card, with savings up to $6,000 a year. Your copay depends on your plan. | LEO Pharma |
| Medicare Part D | Depends on your plan. The co-pay card can't be used. Out-of-pocket costs for covered drugs are capped at $2,100 in 2026 ($2,400 in 2027). | Medicare.gov |
| Medicaid | Your state Medicaid program sets any copay. Ask your pharmacist or state Medicaid office. | Medicaid.gov |
The U.S. list price is the same per gram for both pack sizes: $1,367.13 for one 60 g can and $2,734.24 for two cans, about $22.79 a gram, as LEO Pharma reported to Texas for 2026 (Texas DSHS). That is the maker's wholesale price before discounts. Enstilar has no fixed monthly amount, so we compare prices per gram.
Enstilar cost with Medicare in 2026
In 2026, Part D plans can charge a deductible of up to $615, and once your out-of-pocket spending on covered Part D drugs reaches $2,100 ($2,400 in 2027), you pay nothing more for covered drugs for the rest of the year. Whether your plan covers Enstilar, and what you pay, depends on the plan. The LEO Pharma co-pay card can't be used with Medicare, but Extra Help can lower costs for people with limited income.
| Medicare Part D | What Enstilar costs | Source |
|---|---|---|
| Part D deductible | No Medicare drug plan may have a deductible above $615 in 2026. Some plans have none. | Medicare.gov |
| Yearly out-of-pocket cap | Once your out-of-pocket spending on covered Part D drugs reaches $2,100 in 2026 ($2,400 in 2027), you pay nothing more for covered drugs that year. | Medicare.gov |
Enstilar coupons and savings programs
We show the programs that usually fit, cheapest first where we know the price. Private insurance means a plan through work or one you buy yourself. Programs set their own rules, so check the terms before you count on one. We don't save this choice.
Checking more than one medicine? Use the free Medicare Drug Cost Check.
eDrugSearch does not offer its own Enstilar coupons. These are the real savings programs, run by the drug's maker and by Medicare:
- LEO Pharma CONNECT Co-Pay Card: for people with commercial (private or employer) insurance. Eligible patients pay as little as $30 per Enstilar prescription, with savings of up to $6,000 a year and up to 12 fills per calendar year. Not for anyone enrolled in a state or federally funded health program, such as Medicare (including Part D), Medicaid, Medigap, VA, DOD, TRICARE or CHIP. One card per patient; it can't be combined with other offers. Request or activate a card on the Enstilar site or call 1-877-678-7494. (Enstilar.com)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Is there a generic Enstilar?
No. No generic Enstilar foam is sold in the U.S. The FDA approved Glenmark's generic calcipotriene and betamethasone dipropionate foam in March 2023, but FDA records list it as discontinued, and the FDA's drug listing shows only LEO Pharma's Enstilar foam. Generic ointment and suspension with the same ingredients are sold; they're different products.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 50 mcg/g + 0.5 mg/g | No | — |
Outside the U.S.: In Canada, Enstilar is sold under the same name by LEO Pharma. Online pharmacies abroad may also sell other calcipotriol and betamethasone products; those are not FDA-approved, and the price table labels them that way.
Source: Drugs@FDA: ANDA 214688 (Glenmark), marketing status Discontinued. As of Nov 5, 2026.
Compare Enstilar with similar drugs
Other prescription skin medicines on eDrugSearch. Otezla is a pill for plaque psoriasis; Eucrisa and Opzelura are creams or ointments for other skin conditions. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Otezlaapremilast | Psoriasis and psoriatic arthritis medicine (PDE4 inhibitor) | From $0.46 per tablet | See prices |
| Eucrisacrisaborole | Skin ointment for eczema (topical PDE-4 inhibitor) | From $2.92 per g | See prices |
| Opzeluraruxolitinib | Skin cream for eczema and vitiligo (topical JAK inhibitor) | From $13.26 per g | See prices |
Lowest price per unit, before shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Enstilar used for?
Enstilar (calcipotriene and betamethasone dipropionate) combines a vitamin D analog with a corticosteroid. According to its FDA label (DailyMed), it is used:
- On the skin, to treat plaque psoriasis in people 12 years and older.
Enstilar is a foam in a 60 g spray can. The label says it's used once daily for up to 4 weeks, until the psoriasis is under control, with no more than 60 grams every 4 days. It is for use on the skin only, not on the face, groin or armpits. The foam is flammable, so the label warns to avoid fire, flame and smoking during and right after use. It has no boxed warning. The label warns about high calcium levels in blood or urine, adrenal gland effects from the steroid, allergic skin reactions and eye problems. Your prescriber decides which medicine is right for you.
Is it safe to order Enstilar from Canada?
Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress has said enforcement against individuals should focus on imports that pose a significant threat to public health (Federal Food, Drug, and Cosmetic Act section 804(j)(1), 21 U.S.C. 384(j)(1)). You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, Enstilar foam is sold under the same name by LEO Pharma (Health Canada). Canadian packs list the strength as calcipotriol 50 mcg and betamethasone 0.5 mg (as betamethasone dipropionate) per gram; calcipotriol is the name used outside the U.S. for calcipotriene. U.S. packs list the same amounts as 0.005% calcipotriene and 0.064% betamethasone dipropionate.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Frequently asked questions
How much does Enstilar cost without insurance?
The U.S. list price is $1,367.13 for one 60 g can and $2,734.24 for two cans (about $22.79 a gram), as reported by LEO Pharma to Texas for 2026. In our latest check (Nov 2, 2026), licensed pharmacies abroad charged from $2.21 per g for brand Enstilar, before shipping.
Is there an Enstilar coupon or copay card?
Yes, for commercial insurance. With the LEO Pharma CONNECT co-pay card, eligible patients pay as little as $30 per prescription, with savings up to $6,000 a year and up to 12 fills a year. It can't be used by people in state or federally funded programs such as Medicare or Medicaid.
Is there a generic version of Enstilar?
No generic Enstilar foam is sold in the U.S. The FDA approved a generic foam from Glenmark in 2023, but FDA records list it as discontinued. Generic calcipotriene and betamethasone dipropionate ointment and suspension are sold, but they're different products from the foam. The generic name for Enstilar is calcipotriene and betamethasone dipropionate.
How much does Enstilar cost with Medicare?
It depends on your Part D plan. In 2026, plans can have a deductible of up to $615, and out-of-pocket costs for covered drugs are capped at $2,100 ($2,400 in 2027). The LEO Pharma co-pay card can't be used with Medicare, but people with limited income can apply for Extra Help.
Why is Enstilar so expensive?
Enstilar is a brand-name product with no generic foam on sale in the U.S. Its U.S. list price, the maker's wholesale price before discounts, is $1,367.13 for one 60 g can, as LEO Pharma reported to Texas for 2026. What you pay depends on your insurance, and the LEO Pharma co-pay card can lower it for people with commercial insurance.
Can I buy Enstilar over the counter?
No. Enstilar is a prescription medicine in the U.S., and pharmacies abroad that we list also require a prescription. Your prescriber decides which medicine is right for you.
Is Enstilar the same as Taclonex?
No. Both are made by LEO Pharma and contain calcipotriene and betamethasone dipropionate, but Taclonex is an ointment or suspension and Enstilar is a foam. The FDA approved them as separate products, so a pharmacist can't swap one for the other without your prescriber.
How long does a can of Enstilar last?
It depends on how much skin is treated. The label limits use to 60 grams every 4 days, so at that maximum one 60 g can lasts 4 days. The label also says to throw away unused foam 6 months after the can is opened. We compare prices per gram; your prescriber decides how much you use.
Sources
- ENSTILAR U.S. prescribing information (DailyMed) (LEO Pharma, label effective 2021-10-18 (SPL version 15))
- Texas DSHS: 2026 annual WAC report (Enstilar NDC 50222-0302-60 $1,367.13; 50222-0302-66 $2,734.24)
- Enstilar.com: Patient Savings Program (LEO Pharma CONNECT co-pay card) (as little as $30, up to $6,000 a year, checked 2026-11-05)
- Drugs@FDA: ANDA 214688 (Glenmark generic foam) (approved 2023-03-21, marketing status Discontinued, checked 2026-11-05)
- Drugs@FDA: Enstilar NDA 207589 (approved 2015-10-16)
- FDA NDC Directory: calcipotriene and betamethasone products (checked 2026-11-05)
- Health Canada Drug Product Database: Enstilar (DIN 02457393)
- Medicare.gov: Part D drug costs (deductible up to $615 and $2,100 out-of-pocket threshold in 2026)
- Medicaid.gov: cost sharing
- Social Security: Medicare Extra Help
- Medicare Prescription Payment Plan
- FDA: personal importation
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.