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Breztri Aerosphere Price (budesonide, glycopyrrolate and formoterol fumarate)
As of Nov 5, 2026, brand Breztri Aerosphere 160/9/4.8 mcg costs from $457.17 for 90 days at licensed pharmacies abroad (ships from India; packs made for other countries are not FDA-approved), vs. $2,053.29 at the U.S. list price.
- Lowest international online pharmacy price
- $149.07 per inhaler Lowest price$457.17 for 90 days (3 inhalers), shipping included · brand Breztri Aerosphere 160/9/4.8 mcg, not FDA-approved · ships from India
- Lowest U.S. online pharmacy price
- $753.00 per inhaler$2,264 for 90 days (3 inhalers), shipping included · FDA-approved brand Breztri Aerosphere 160/9/4.8 mcg · ships within the U.S.
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Name check: Sold as Trixeo or Riltrava Aerosphere in Europe and the U.K. Labels abroad list the delivered dose, 160/7.2/5 mcg, which matches the U.S. 160/9/4.8 mcg strength.
Compare Breztri Aerosphere prices from licensed pharmacies
For comparison U.S. pharmacy list price: $2,053.29 for 90 days ($684.43 per inhaler), brand Breztri Aerosphere 160/9/4.8 mcg before insurance. The prices below are from U.S. pharmacies that publish cash prices and from licensed online pharmacies outside the U.S.
| Pharmacy | Medication | Price | Shipping & delivery | Total (90 days) | Buy |
|---|---|---|---|---|---|
| Lowest per inhalerOnline pharmacy A | Breztri Aerosphere (160mcg/7.2mcg/5mcg) 160mcg/9mcg/4.8mcg160/9/4.8 mcg · brand · Filled in IndiaMade for sale in India.Maker listed by pharmacy: AstraZeneca | $447.22for 3 inhalers$149.07 per inhaler | $9.95Pharmacy's estimate: 4–6 weeks | $457.17 for 90 days= $457.17 for 90 daysSave 78%incl. $9.95 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per inhalerOnline pharmacy A | Breztri Aerosphere (160mcg/7.2mcg/5mcg) 160mcg/9mcg/4.8mcg160/9/4.8 mcg · brand · Filled in United KingdomMaker listed by pharmacy: AstraZeneca | $537for 3 inhalers$179.00 per inhaler | $9.95Pharmacy's estimate: 4–6 weeks | $546.95 for 90 days= $546.95 for 90 daysSave 73%incl. $9.95 shippingChecked Nov 14 | See pharmacy (members) Members see the pharmacy |
| Lowest per inhalerLicensed Canadian pharmacy B | Breztri Aerosphere (160mcg/7.2mcg/5mcg)160/9/4.8 mcg · brand · Filled in CanadaMaker listed by pharmacy: Astra-Zeneca Canada Inc. | $607.45for 3 inhalers$202.48 per inhaler | $9.95Pharmacy's estimate: 3–6 weeks | $617.40 for 90 days= $617.40 for 90 daysSave 70%incl. $9.95 shippingChecked Nov 14 | See pharmacy (members) Members see the pharmacy |
| Lowest per inhalerOnline pharmacy A | Breztri Aerosphere (160mcg/7.2mcg/5mcg) 160mcg/9mcg/4.8mcg (United States pack, ships from Canada)160/9/4.8 mcg · brand · Filled in CanadaMaker listed by pharmacy: AstraZenecaMade for United States | $657for 3 inhalers$219.00 per inhaler | $9.95Pharmacy's estimate: 4–6 weeks | $666.95 for 90 days= $666.95 for 90 daysSave 68%incl. $9.95 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per inhalerOnline pharmacy C | Breztri Aerosphere (160mcg/7.2mcg/5mcg) 160mcg/9mcg/4.8mcg Aerosol, Metered Dose160/9/4.8 mcg · brand · Filled in CanadaMaker listed by pharmacy: Astrazeneca | $669.39for 3 inhalers$223.13 per inhaler | FreePharmacy's estimate: 2–3 weeks | $669.39 for 90 days= $669.39 for 90 daysSave 67%incl. $0 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per inhalerOnline pharmacy C | Trixeo Aerosphere (162mcg/7.2mcg/5mcg) 160mcg/9mcg/4.8mcg Aerosol, Metered Dose160/9/4.8 mcg · brand · Filled in United KingdomMaker listed by pharmacy: Astra-Zeneca | $908.79for 3 inhalers$302.93 per inhaler | FreePharmacy's estimate: 2–3 weeks | $908.79 for 90 days= $908.79 for 90 daysSave 56%incl. $0 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per inhalerLicensed U.S. pharmacy D | Breztri Aerosphere 160-9-4.8 mcg Inhaler - 10.7g160/9/4.8 mcg · brandMaker listed by pharmacy: AstraZeneca Pharmaceuticals LPShips from United StatesShips within the U.S. (no customs) · checked Nov 5, 2026 | $753per 1 inhaler · 3 packs = $2,259$753.00 per inhaler | $5Pharmacy's estimate: 2–8 business days | $2,264 for 90 days= $2,264 for 90 daysincl. $5 shippingChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per inhalerOnline pharmacy E | Budesonide/Glycopyrrolate/Formoterol Fumarate 160mg/9mg/4.8mgNot FDA-approvedMade for sale in another country. It has the same active ingredient as the brand, but the FDA hasn't reviewed this maker's version.160 mg/9 mg/4.8 mg · generic · Filled in IndiaMade for sale in India.Maker listed by pharmacy: Cipla | $44.94for 120 inhalers$0.37 per inhalerOver 3-month supply | $14.95Pharmacy's estimate: 4–6 weeks | $59.89 for 3600 days= $1.50 for 90 daysWorked out from a 3600-day orderChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per inhalerOnline pharmacy F | Trixeo Aerosphere 160mcg/7.2mcg/5mcg (160mcg/9mcg/4.8mcg) Aerosol, Metered Dose (UK/EU pack, ships from United Kingdom)160 mcg/7.2 mcg/5 mcg (160 mcg/9 mcg/4.8 mcg) · brand · Filled in United KingdomMaker listed by pharmacy: Maker not shown by pharmacyMade for UK/EU | $102.04for 120 inhalers$0.85 per inhalerOver 3-month supply | Fee not publishedDelivery time not stated | $102.04 for 3600 days= $2.55 for 90 days+ shippingWorked out from a 3600-day orderChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
| Lowest per inhalerOnline pharmacy E | Breztri Aerosphere 160mcg/7.2mcg/5mcg160 mcg/7.2 mcg/5 mcg · brand · Filled in AustraliaMaker listed by pharmacy: AstraZeneca | $236.54for 120 inhalers$1.97 per inhalerOver 3-month supply | $14.95Pharmacy's estimate: 4–6 weeks | $251.49 for 3600 days= $6.29 for 90 daysWorked out from a 3600-day orderChecked Nov 5 | See pharmacy (members) Members see the pharmacy |
No prices match those filters.
Buying from a pharmacy outside the U.S.? Read Is it safe to order Breztri Aerosphere from Canada?
90-day cost = 3 inhalers at the usual dose of 1 a month, bought as one order of whole packs with one shipping fee. 90-day cost is worked out from each pharmacy's real order size so different pack sizes compare fairly. Orders are kept within a 3-month supply (92 days); a pack that is larger than that is marked and not used for the lowest price at the top of this page. Prices checked Nov 5, 2026 on each pharmacy's website, in U.S. dollars. Savings compare with the U.S. list price of the same strength (160/9/4.8 mcg); rows for other strengths show no saving. The lowest price at the top of this page uses only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price is the pharmacy's own price for one pack, as shown on its website (converted to U.S. dollars when it prices in Canadian dollars). Delivery is the pharmacy's own estimate for the shipping option shown, not a promise; some pharmacies count from when they receive your prescription or ship the order. Total = the packs needed + shipping. When those packs don't add up to exactly 90 days, the row shows what that order costs and, under it, what it works out to for 90 days; we sort by the 90-day amount so pack sizes compare fairly. Prices change often; confirm at checkout. U.S. rows: the cash price a U.S. pharmacy published on its own website on the date shown, for whole fills, plus its standard shipping; no insurance or discount cards. “Fee not published” means the pharmacy doesn’t show its shipping fee before checkout, so that row’s total is the medicine price only.
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90-day prices from 3 licensed pharmacies abroad shipping to the U.S.: $457.17 to $908.79, any strength, shipping included.
Jump to: Medicare · Maker savings · Generic Breztri Aerosphere · Similar drugs · Uses · FAQ
Breztri Aerosphere inhaler (budesonide, glycopyrrolate and formoterol) for COPD and asthma. Each inhaler holds 120 puffs. No U.S. generic.
Breztri Aerosphere price by strength
| Strength | Lowest brand90 days | Price per inhaler |
|---|---|---|
| Breztri Aerosphere 160/9/4.8 mcg | $457.17 | $149.07 |
Lowest 90-day cost with shipping at licensed pharmacies shipping to the U.S. now, counting only packs whose maker the pharmacy names, or whose product country and ships-from country it states. Price per inhaler is for that lowest pack, before shipping. Prices checked Nov 5, 2026.
Cheapest ways to get Breztri Aerosphere 160/9/4.8 mcg
The cheapest ways we found to get brand Breztri Aerosphere 160/9/4.8 mcg (prices checked Nov 5, 2026). The lowest 90-day cost is shaded green.
| Way to buy | Cost | Details |
|---|---|---|
| Licensed online pharmacy abroad | $457.17 for 90 days | Brand Breztri Aerosphere 160/9/4.8 mcg, ships from India, not FDA-approved (made for another country). Shipping included, checked Nov 5, 2026. See all prices |
| U.S. pharmacy cash price | $2,264 for 90 days | FDA-approved brand Breztri Aerosphere 160/9/4.8 mcg, ships within the U.S. (no customs). Shipping included, checked Nov 5, 2026. See all prices |
| U.S. list price | $2,053.29 for 90 days | Brand Breztri Aerosphere before insurance. Pharmacies may charge more. |
| Medicare Part D | Depends on your plan | Your plan’s drug list and coverage phase set your cost. Medicare costs |
Costs abroad and at U.S. pharmacies are for one order closest to 90 days, shipping included, from the price table above. Programs set their own rules, so check the terms before you count on one.
How much does Breztri Aerosphere cost without insurance?
Without insurance, Breztri Aerosphere costs $684.43 for a 30-day supply at the U.S. list price, or about $2,053.29 for 90 days. Licensed pharmacies abroad charged from $457.17 for 90 days of brand Breztri Aerosphere 160/9/4.8 mcg in our latest check (Nov 5, 2026), shipping included. Astrazeneca $35 cap: AstraZeneca says eligible patients, including people who are uninsured, pay no more than $35 a month. Terms apply; call 1-800-236-9933 to check eligibility (AstraZeneca).
Breztri Aerosphere cost with Medicare
In 2026, a Medicare drug plan (Part D) can charge a deductible of up to $615, and once you've spent $2,100 out of pocket on covered drugs, you pay nothing more for covered drugs that year ($2,400 in 2027) (Medicare.gov). What you pay for Breztri Aerosphere depends on your plan's drug list and your coverage phase. If your income is limited, Extra Help lowers drug costs: in 2026 you pay no more than $5.10 for a generic and $12.65 for a brand-name drug, with income under $23,940 ($32,460 for a married couple) and resources under $18,090 ($36,100 for a couple) (CMS). The free Medicare Prescription Payment Plan spreads costs into monthly payments, but it doesn't lower the total.
| Medicare Part D | What Breztri Aerosphere costs | Source |
|---|---|---|
| Part D deductible (2026) | Up to $615 a year, depending on your plan | Medicare.gov |
| Yearly out-of-pocket cap (2026) | $2,100 for covered Part D drugs ($2,400 in 2027) | Medicare.gov |
Breztri Aerosphere cost with insurance
With private or employer insurance, what you pay for Breztri Aerosphere depends on your plan's drug list, deductible and copay. As little as $0 for each 30-day supply (1 inhaler) with the BREZTRI Zero Pay Card, subject to a maximum savings limit (AstraZeneca).
Breztri Aerosphere patient assistance program
AstraZeneca runs AZ&Me Prescription Savings Program. Who qualifies: U.S. residents treated by a U.S.-licensed prescriber who have no commercial (private or employer) insurance, with household income at or below 300% of the federal poverty level for most medicines ($47,880 for 1 person in the 48 states, effective January 26, 2026). People with Medicare must not be eligible for or enrolled in Extra Help. We couldn't confirm on the program's own pages that Breztri Aerosphere is on its current list (checked 2026-10-29), so call 1-800-292-6363 to ask before you apply.
Is there a generic Breztri Aerosphere?
No. There is no FDA-approved generic of Breztri Aerosphere, and only AstraZeneca's brand is sold in the U.S. AstraZeneca has patents listed with the FDA that run to 2030, 2031 and 2038. Patent dates don't tell you exactly when a generic will launch.
| Strength | U.S. generic | Makers | Since |
|---|---|---|---|
| 160/9/4.8 mcg | No | — | |
| 160/18/4.8 mcg | No | — |
Outside the U.S.: Sold abroad as Breztri Aerosphere (Canada) and Trixeo Aerosphere or Riltrava Aerosphere (Europe, U.K.), all made by AstraZeneca.
Source: FDA Orange Book: Breztri Aerosphere (NDA 212122). As of Oct 26, 2026.
Breztri Aerosphere FAQ
How much does Breztri cost with Medicare?
It depends on your Part D plan. In 2026, plans can have a deductible of up to $615, and out-of-pocket costs for covered drugs are capped at $2,100 a year ($2,400 in 2027). AstraZeneca's co-pay help can't be used with Medicare, but it says people with Medicare Part D may qualify for AZ&Me. People with limited income can also apply for Extra Help.
How much does Breztri cost without insurance?
AstraZeneca lists the U.S. price at $684.43 for a 30-day supply, which is one 120-puff inhaler, or about $2,053 for 90 days. Pharmacies may charge more. As of Nov 5, 2026, licensed pharmacies abroad we compared sold 90 days (3 inhalers) of brand Breztri Aerosphere 160/9/4.8 mcg from $457.17, shipping included.
Is there a generic Breztri?
No. The FDA has not approved a generic of Breztri Aerosphere, and only AstraZeneca's brand is sold in the U.S. AstraZeneca has patents listed with the FDA that run to 2030, 2031 and 2038.
Is Breztri a prescription medicine?
Yes. Breztri Aerosphere needs a prescription in the U.S. Licensed pharmacies abroad also ask for a valid prescription from your own prescriber.
Is there a patient assistance program for Breztri Aerosphere?
AstraZeneca runs AZ&Me Prescription Savings Program. Who qualifies: U.S. residents treated by a U.S.-licensed prescriber who have no commercial (private or employer) insurance, with household income at or below 300% of the federal poverty level for most medicines ($47,880 for 1 person in the 48 states, effective January 26, 2026). People with Medicare must not be eligible for or enrolled in Extra Help. We couldn't confirm on the program's own pages that Breztri Aerosphere is on its current list (checked 2026-10-29), so call 1-800-292-6363 to ask before you apply.
How do I get Breztri for $35?
AstraZeneca says eligible patients pay no more than $35 a month for its inhalers, including Breztri, and its 2024 announcement says this includes people who are uninsured or underinsured. Terms apply. Call AstraZeneca at 1-800-236-9933 to ask about eligibility. People in federal government insurance programs, such as Medicare, can't get its co-pay support.
Is Breztri from Canada or Europe the same as in the U.S.?
It is made by AstraZeneca in each country. In Canada it is sold as Breztri Aerosphere; in Europe and the U.K. it is sold as Trixeo Aerosphere or Riltrava Aerosphere. Their labels list the dose that leaves the mouthpiece (160/7.2/5 mcg), so the numbers look different, but it is the same as the U.S. 160/9/4.8 mcg strength.
What is the difference between Breztri 160/9/4.8 and 160/18/4.8?
Both have the same amounts of budesonide (160 mcg) and formoterol fumarate (4.8 mcg) per puff. The 160/18/4.8 mcg strength has twice as much glycopyrrolate: 18 mcg instead of 9 mcg. The FDA label lists 160/9/4.8 mcg for COPD and 160/18/4.8 mcg for asthma. Your prescriber decides which medicine is right for you.
Savings programs from the maker
eDrugSearch doesn't run its own savings program for Breztri Aerosphere. These are the AstraZeneca and Medicare programs we could verify on their own sites:
- BREZTRI Zero Pay Card: for people with commercial (private or employer) insurance. Eligible patients may pay as little as $0 for each 30-day supply (1 inhaler), subject to a maximum savings limit. Not for Medicare Part D, Medicaid, Medigap, VA or other state or federal programs, and not for people paying cash as uninsured. One card per person. (Breztri savings)
- AstraZeneca $35 monthly inhaler cap: AstraZeneca says eligible patients, including people who are uninsured or underinsured, pay no more than $35 a month for its inhalers, including Breztri. Terms apply; call 1-800-236-9933. Medicare and Medicaid enrollees can't use it, and a cash purchase won't count toward a Medicare plan's deductible or the $2,100 yearly cap. With private insurance, ask your plan whether a cash purchase counts toward your deductible. (AstraZeneca)
- AZ&Me patient assistance: AstraZeneca says people who are uninsured or have Medicare Part D and can't afford Breztri may qualify for its patient assistance program, AZ&Me. Check eligibility on its site or call 1-833-458-0440. (AZ&Me)
- Medicare Extra Help: if you have Medicare and limited income, Extra Help lowers what you pay for prescriptions. (Social Security)
- Medicare Prescription Payment Plan: a free Medicare option that spreads your drug costs into monthly payments across the year. It doesn't lower the total, but it can make costs easier to manage. (Medicare.gov)
Compare Breztri Aerosphere with similar drugs
Other inhalers people often compare with Breztri, including Trelegy Ellipta, another three-in-one inhaler. Prices are for each drug's lowest-priced strength.
| Drug | Type | Lowest price we found | Link |
|---|---|---|---|
| Trelegy Elliptafluticasone furoate, umeclidinium and vilanterol | COPD and asthma inhaler (a steroid plus two long-acting bronchodilators) | $187.71 for 90 days | See prices |
| Symbicortbudesonide and formoterol | Asthma and COPD inhaler (inhaled steroid plus long-acting bronchodilator) | $75.61 for 90 days | See prices |
| Breo Elliptafluticasone furoate and vilanterol | Asthma and COPD inhaler (a steroid plus a long-acting bronchodilator) | $135.95 for 90 days | See prices |
| Spiriva Respimattiotropium bromide | COPD and asthma maintenance inhaler (long-acting anticholinergic bronchodilator) | $208.99 for 90 days | See prices |
Lowest 90-day price including shipping, from licensed pharmacies shipping to the U.S., any strength. Only your doctor can decide whether another drug is right for you.
What is Breztri Aerosphere used for?
Breztri Aerosphere combines three medicines in one inhaler: budesonide (an inhaled corticosteroid), glycopyrrolate (an anticholinergic) and formoterol fumarate (a long-acting beta2-agonist). According to its FDA label (DailyMed), it is used for:
- Long-term (maintenance) treatment of chronic obstructive pulmonary disease (COPD) in adults.
- Long-term (maintenance) treatment of asthma in adults and children 12 years and older.
Breztri is not a rescue inhaler and is not used for sudden breathing problems. It comes in two strengths: the label lists 160/9/4.8 mcg for COPD and 160/18/4.8 mcg (approved in April 2026) for asthma. The labeled dose is 2 puffs twice a day, so a 120-puff inhaler lasts 30 days. Your prescriber decides which medicine is right for you.
Is it safe to order Breztri Aerosphere from Canada?
Many Americans do, but U.S. law and customs rules apply. Federal law generally doesn't allow individuals to import prescription drugs, though under its personal importation policy the FDA has long used enforcement discretion for some personal-use shipments, generally no more than a three-month supply (FDA). Congress declared in FD&C Act 804(j)(1), 21 U.S.C. 384(j)(1), that enforcement against individuals should focus on imports posing a significant threat to public health. You need a prescription from your doctor. New U.S. Customs rules for mailed orders start January 20, 2027. In Canada, AstraZeneca sells it as Breztri Aerosphere; in Europe and the U.K. it is sold as Trixeo Aerosphere or Riltrava Aerosphere. Labels there list the dose that leaves the mouthpiece (160/7.2/5 mcg), which is the same medicine as the U.S. 160/9/4.8 mcg strength.
Read our guide to buying prescription drugs from Canada and what the 2027 customs rules mean. Compare licensed Canadian pharmacies.
Sources
- Breztri: Cost and affordability (AstraZeneca) (list price $684.43 per 30-day supply (RedBook price as of February 2026), checked 2026-10-26)
- BREZTRI Zero Pay Card: eligibility and terms (AstraZeneca) (checked 2026-10-26)
- AstraZeneca: respiratory inhaler affordability ($35 per month cap) (checked 2026-10-26)
- AstraZeneca: $35 per month cap on out-of-pocket costs for inhalers (Business Wire) (March 18, 2024)
- AZ&Me patient assistance (AstraZeneca)
- BREZTRI AEROSPHERE U.S. prescribing information (DailyMed) (revised April 2026)
- FDA Orange Book: Breztri Aerosphere (NDA 212122) patents
- FDA Orange Book: Breztri Aerosphere 160/18/4.8 mcg (NDA 212122, product 002) (new-strength exclusivity to April 27, 2029)
- Health Canada product monograph: BREZTRI AEROSPHERE (AstraZeneca Canada Inc.) (revised April 14, 2023)
- Trixeo Aerosphere summary of product characteristics (U.K. eMC)
- European Medicines Agency: Riltrava Aerosphere
- FDA: personal importation
- Medicare.gov: costs in drug plans (2026 deductible up to $615; out-of-pocket cap $2,100 in 2026, $2,400 in 2027)
eDrugSearch does not sell medication, and this is not medical advice. Prices change often; confirm the price at checkout. Talk with your doctor or pharmacist before changing how you get your medication.
