Quitting smoking is no easy task. Once your body becomes dependant on cigarettes, it starts to shut down when you try to quit. People who are in the process of quitting often become irritable, have trouble sleeping, gain weight, and find it hard to focus throughout the day.

This is the body’s defense against the mind’s decision to quit. Of course, the best solution is power through until the withdrawals of nicotine wear off. That’s much easier said than done, though, which is why many people use smoking cessation drugs to support their quitting process. If you’ve been thinking about quitting, make sure you have something to help you do so.

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Here’s a list of the top ten smoking cessation drugs to choose from. Note: some of them can be combined with one another, while others are best to use on their own.

1.) Clonidine

Just as the pills mentioned thus far help soothe withdrawal effects and boost a person’s mood, Clonidine does the same. But, it also helps treat high blood pressure.

This great for people who use smoking as a way to ease stress or calm down. You don’t have to reach for a cigarette when you feel anxious anymore. You can get a prescription for Clonidine instead to help you stay on the path toward success when quitting smoking.

2.) Bupropion

The next pill you can take to fix your smoking habit is Bupropion. This prescription medicine is actually an antidepressant. However, the effects of Buproprion do wonders for a person’s withdrawal symptoms and cravings.

The pill attacks chemicals released by the brain when it starts to crave nicotine. This starts to reverse the need for smoking until you no longer feel an urge to do so.

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3.) Varenicline

While it’s nice to find topical solutions and simple nicotine replacements, some smokers who are trying to quit need more support. If this sounds like you, look into stop smoking pills like Varenicline.

Varenicline (Chantix) is a prescription medicine that focuses on the nicotine receptors in the brain. This provides a two-for-one kind of result. Targeting the nicotine receptors means you will feel less pleasure than before from smoking, and it will also lessen the effects of nicotine withdrawal.

4.) Nortriptyline

If you’re looking for something other than Varenicline and Buproprion, try Nortriptyline. This is another antidepressant that can help you feel good as you work to overcome the withdrawal stage of quitting smoking.

Nortriptyline works best when you start taking it before quitting. As such, you need to create a plan with your doctor to line everything up well. Tell them when you plan to start the quitting process and make sure you do so well ahead of time so you can get a good amount of Nortriptyline in your system.

5.) Nicotine Gum

The thing about smoking is that it creates mental habits, not just physical cravings.

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Many smokers have a sort of oral fixation they can’t shake when they try to quit smoking. They’re used to having a cigarette in their mouth, so they need something else.


That’s where nicotine gum comes in – it’s a great way to fight the body’s physical and mental defenses. Nicotine gum gives the body small doses of nicotine to curb its cravings, and it keeps the mouth entertained, too.

6.) Nicotine Patch

Nicotine patches are topical nicotine treatments. You place a patch on your skin which releases small doses of the drug into your system. The point is to use these as a replacement for cigarettes until your body no longer craves the nicotine at all.


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This is accomplished by lowering the dose of nicotine in your patches. Smokers often start with a high-dosage nicotine patch and maybe a few cigarettes throughout the day. Then, they stop the cigarettes and rely on the patch, then quit using the patch altogether.

7.) Nicotine Spray

Nicotine spray is one of the more interesting medicines to fight quit smoking withdrawal. This is a prescription treatment that you shoot into your nose.


The spray releases nicotine into the body, similar to the effects of nicotine gum and a nicotine patch. This medication, though, is something people use on a more regular basis. Nicotine spray can be used one or two times every hour throughout the day.

Also, be aware that it may cause coughing, a runny nose, or watery eyes.

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8.) Antidepressants

The antidepressants listed above are just a handful of the smoking cessation drugs out there. There are also natural antidepressants you can use to get the same results, in addition to the wide range of prescription drugs available.

9.) Nicotine Inhalers

Another form of nicotine replacement therapy is a nicotine inhaler. This releases nicotine into the body through the mouth. Like the stop smoking aids listed above, this is meant to help the body curb its cravings until it doesn’t feel a desire for nicotine anymore.


10.) Transcranial Magnetic Stimulation

When nicotine replacements and quitting smoking pills aren’t working, try transcranial magnetic stimulation (TMS). This targets the brain’s neural activity through non-invasive stimulation.

TMS helps fight the cravings for nicotine and the effects of withdrawal. It targets the receptors in the brain through magnetic devices that have been approved by the FDA. The best results from TMS occur when the treatment is repetitive and ongoing.

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Find the Right Smoking Cessation Drugs for You

It’s one thing to read about different smoking cessation drugs and another to find which one is your key to quitting smoking. Do a bit of research on all your options before you commit to one method of fighting quit smoking withdrawal effects.

Be sure to talk to your doctor, too.

When you’re ready to purchase your quitting tools of choice, use our system to help you find the lowest prices!