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Is Amgen’s new osteoporosis drug worth 20x more than current choices? - August 12, 2009
With the best-selling osteoporosis drug Fosamax on trial amid allegations that it causes “jaw death” in patients, you might think healthcare consumers would rejoice at the prospect of a new alternative to Fosamax on the market. You might think that — until you look at the price. The new drug, Amgen’s Prolia (denosumab), is up for approval by an FDA advisory committee this week. The aspect of Prolia that has received the most attention is that it is a product of biotechnology. It is a new class of drug, a “fully human monoclonal antibody” designed to target a protein that causes bone loss. Studies indicate that it works as well as or slightly better than Fosamax and other bisphosphonates, such…Read More
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