Should You Take Linzess for Irritable Bowel Syndrome?

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People living with Irritable Bowel Syndrome (IBS) know that it’s a constant and chronic struggle. And it isn’t a rare disorder, either. It’s thought that up to 15% of the world population suffers from IBS, which is around 785 million people.

But with many different symptoms with varying intensities, not all treatments for IBS are going to work for everyone. Taking Linzess is one treatment option that some people have success with.

What is Linzess exactly? How will it affect your body? Are there side effects?

Do you struggle with Irritable Bowel Syndrome #IBS? #Linzess is the brand name of the medication #linaclotide that could be a viable option for you. Here's why... #constipation #BloatMuch #StomachDisease #DrugPrices Click To Tweet

We are going to answer all these questions and more in this article. If you or a loved one has been prescribed Linzess, keep reading to get all the important information about this drug.

What Is Irritable Bowel Syndrome?

Let’s start with understanding IBS.

The cause of IBS isn’t known. Some theories suggest muscle abnormalities in the digestive system. Another theory suggests that neural abnormalities could result in IBS. A third theory suggests that changes to the microbiome in your stomach and gut could be a cause of IBS as well.

IBS affects the large intestine. It’s characterized by having one, or all, of the following issues:

  • Bloating
  • Diarrhea
  • Cramping
  • Constipation
  • Mucus in stool
  • Abdominal pain
  • Excessive flatulence

IBS can cause any or all of these symptoms, and sometimes the symptoms can alternate or change in intensity.

What Is Linzess?

Linzess is the brand name of the medication linaclotide. It’s an oral medication that’s prescribed to help manage symptoms of IBS and other bowel issues like chronic constipation.

Specifically, Lizness helps treat symptoms of constipation related to IBS.

You should follow the directions on the prescription given to you by your doctor in terms of dosage. It’s usually taken once per day in the morning around 30 minutes before your first meal of the day.

How Does Linzess Work?

When Linzess enters the body, it induces the intestines to secrete more chloride and water. This helps to soften stool, make it easier to pass bowel movements, and can even help stimulate a bowel movement in the first place.

It can also help reduce pain caused by constipation.

Linzess Side Effects

There are a few side effects to be aware of when taking Linzess. The most common ones include:

  • Gas
  • Diarrhea
  • Abdominal pain
  • Bloating/fullness in the stomach

These common side effects are usually mild and manageable.

Serious Side Effects

However, if you experience any of the following effects, you should stop taking Linzess and speak to a physician as soon as possible:

  • Fainting
  • Dizziness
  • Severe pain
  • Blood in stool
  • Lightheadedness
  • Severe or constant diarrhea

Allergic Reaction

You can also be allergic to Linzess. An allergic reaction to this medication would trigger the following symptoms:

  • Hives
  • Difficulty breathing
  • Facial/throat swelling

If you notice these symptoms, stop taking this medication immediately and speak to a medical professional.

Electrolyte Imbalance

Lastly, Linzess can cause a dangerous electrolyte imbalance. Signs of an electrolyte imbalance include:

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  • Confusion
  • Heart “fluttering”
  • Muscle cramping
  • Muscle weakness
  • Frequent urination
  • Irregular heartbeat
  • Extreme changes in mood

If an electrolyte imbalance goes untreated, it can be fatal or lead to serious and permanent consequences. Speak to your doctor as soon as you notice any of these symptoms when taking Linzess.

Should You Take Linzess for Your IBS Symptoms?

With all that being said: should you take Linzess for your IBS? The answer will depend on your specific IBS symptoms and experiences.

While constipation and pain from constipation are common symptoms of IBS, not everyone with IBS suffers from these things. If you don’t experience constipation from IBS, Linzess won’t be helpful for managing your IBS.

If, however, you find that constipation is one of the main symptoms you experience and it affects your everyday life, then Linzess could be helpful for you. Be sure to talk with your doctor about how you can incorporate this medication into your overall treatment plan.

Other IBS Treatment Options

Linzess is just one option that can help treat, and manage, your IBS symptoms.


One method of treating and managing IBS symptoms is your diet. Diet has a huge impact on our digestive health and can have an even larger impact on IBS symptoms.

Examine your diet to understand what types of food and drink trigger your IBS symptoms. Once you know which foods trigger your symptoms, you can cut out (or at least greatly reduce) the amount that you consume.


Several studies show that getting regular exercise can help reduce symptoms of IBS. Not everyone likes running or jogging, and that’s OK. Try going for a walk, playing fetch with your dog, going to a yoga class, or joining a softball league.

Anything that gets your heart beating and your body moving can help manage IBS symptoms and give you some relief.


Lack of sleep has been linked to worsened IBS symptoms. Unfortunately, IBS symptoms also tend to make it harder for those with IBS to get enough sleep.

Try your best to get enough sleep every night. Have a nighttime routine that helps calm your mind. If sleep is still hard for you, try drinking chamomile tea and lavender lotion, or even taking a melatonin supplement.

Other Medications and Supplements

Speaking of supplements, there are a few other supplements and medications that can help manage IBS. Depending on your symptoms, your doctor could recommend taking a fiber supplement.

There are also medications that can help control diarrhea, bloating, and other IBS symptoms. Laxatives might also be recommended.

Linzess for IBS: Bottom Line

If you’re suffering from constipation due to IBS, Linzess is a great option available to you. It can help make your bowel movements smoother and less painful.

Hopefully, this article helped you understand how Linzess may affect your body and your IBS symptoms. If you’d like to learn where to purchase Linzess at the best price, check out our price comparison tool.

You can also check our blog for other informative articles about medications, health conditions, and more.

About Cary Byrd

eDrugSearch founder, Cary Byrd, has been called an “e-health innovator” by MarketIntellNow, interviewed by top pharmaceutical industry journalists, invited to Matthew Holt’s Health 2.0 Conference and a Consumer Report's health summit, and highlighted on numerous health blogs.


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