5 Essential Things You Should Know About Aczone and How It Works

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Did your last acne gel leave your skin dry, red, and peeling like a raw onion that made you want to cry? If so, you might want to try out Aczone, one of the most popular acne gels that has come out in the last few years.

This popular acne gel has the reputation as one of the most gentle but effective topical acne treatments on the market. Dermatologists all over the world are prescribing it and reporting good results.

Compared with other well-known acne gels such as benzoyl peroxide or Retin-A, the gel’s drying effect on the skin is known to be less intense. This makes it ideal for people with sensitive or dry skin, and it is often also prescribed with other acne medications.

If you are interested in trying out Aczone today, here are five essential things you should know about it before you try it.

How Does Aczone Work?

Aczone’s main ingredient is dapsone, a drug that was traditionally used to treat leprosy. However, due to its anti-inflammatory and anti-microbial agents, dermatologists have found it to be incredibly effective in reducing both inflammatory and non-inflammatory acne lesions.

Although Allergan, the manufacturer, does not call the gel an antibiotic cream, dapsone is a sulfone antibiotic, which classifies it as a topical antibiotic. With regular application, it can reduce the number of P. acne (Propionibacterium acnes), a bacteria that lives on most people’s faces that cause acne when stuck in hair follicles with dirt and oil.

Another way this cream treats acne is by mildly drying up the skin which P. acne needs to thrive on. All of this helps reduce the swelling and redness of existing pimples and lead to more even-toned and clearer skin.

One thing to note when using the cream is that it can take up to 12 weeks for you to see full results. Because the gel is more gentle than most other topical acne treatments, dermatologists will usually prescribe it along with other acne medications such as Tretinoin or Epiduo.

The fact that it works slowly is not necessarily a bad thing because if you have sensitive skin, the gel will cause less irritation and dryness.

What Is the Gel’s Success Rate?

In a study done by Allergan, 4,340 patients with moderate acne tried out Aczone gel 7.5 for 12 weeks.

Of those patients, about 29.8% noticed a reduction in their acne lesions. Although 29.8% may not seem like a high number, those who did notice a difference noticed a significant change in their skin. They calculated a 54.6% reduction in inflammatory lesions and 45.1% in non-inflammatory lesions.

As a reminder, no acne gel has ever had a 100% success rate for all its users. Acne is an extremely difficult condition to cure. Its causes vary from person to person, and while medication can alleviate its symptoms, it may still not get rid of its underlying cause. Aczone gel is a medication that is meant to reduce acne lesions, but it will not get rid of the root of the problem.


What Are the Side Effects?

Like most acne medication, this gel has side effects.

Some common side effects that users have reported are dry and itchy skin, but since moisturizers can be used afterward, these effects can be easily minimized.

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If you use benzoyl peroxide, please note that using it together with the cream can cause your skin to turn yellow or orange. One way to go around this is to alternate the medications. Try to use one at night and one during the day or vice versa instead.

Two serious, but less common side effects are decreased oxygen and anemia. The decrease in oxygen can be caused by a particular type of abnormal red blood cell. This is a condition known as methemoglobinemia, and its symptoms are grey or blue lips, nail beds, or mouth.

The other serious side effect is the breakdown of red blood cells known as hemolytic anemia, particularly in people with G6PD deficiency. If you noticed any unusual back pain, dark brown urine, shortness of breath, fever, tiredness or weakness, yellow or pale skin, discontinue the gel and contact your doctor right away.

And with all topical acne gels, make sure you use sunscreen before going out because they will make your skin extra sensitive to the sun.

Who Should Not Use This Gel?

As we just mentioned, people with glucose-6-phosphate dehydrogenase deficiency (G6PD) should not use this gel.

People who have higher than normal levels of methemoglobin in their blood also should avoid this gel.

Last but not least, people who are pregnant or planning to become pregnant and breastfeed should not use this gel. Although there are no known studies about its effects on pregnant women, antibiotic gels are generally not recommended for pregnant women because of its high chance of being passed onto the fetus or infant.

How Much Does It Cost?

Depending on the country you live in and your insurance, the price of this drug will vary. If your insurance covers it, then you do not have to pay anything or pay a small copay. If your insurance does not cover it, however, the gel can cost you more than $600 at your local pharmacy!

Fortunately for you, you can buy it for much less through one of our online retailers.

You Can Beat Acne

If you have acne, but you also suffer from dry skin or rosacea, Aczone might be the right cream for you.

We know what its like to try out an acne medication only to be disappointed but don’t give up. Acne medication is constantly revolutionizing itself, and you never know, the next one might just work. Getting rid of acne takes trial and error and lots of patience. But when you find the right one, it is so worth it. Thousands of people have found great results from using this gel, and you can be one of them.

If you are interested in more in-depth information on other prescribed medication or want to save money on brand-name medications, be sure to check out our website today!

About Cary Byrd

eDrugSearch founder, Cary Byrd, has been called an “e-health innovator” by MarketIntellNow, interviewed by top pharmaceutical industry journalists, invited to Matthew Holt’s Health 2.0 Conference and a Consumer Report's health summit, and highlighted on numerous health blogs.


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