Top 10 Expensive Drugs With Cheaper Alternatives

Categories: Affordable Healthcare, Drug Prices, Drug Savings Tips, Prescription Drugs | Posted On:

When should you opt for the brand name expensive drugs and when should you consider a cheaper generic option? The answer, surprisingly, is more often than you think!

The truth is, more physicians and pharmacists are actually recommending that their patients opt for cheaper generic drugs as opposed to brand name expensive drugs.

They are the same quality and are just as effective, but they don’t come with a fancy unnecessary price upgrade. Don’t Take That Expensive Drug—Take This Generic Instead!

In this post, learn about 10 expensive drugs that you can substitute with equally effective yet much cheaper generic drug alternatives.

For your convenience, we have linked to all medication prices listed within the eDrugSearch database that will help you save even more—up to 90% off U.S. retail drug prices.

1. Dexilant

Dexilant is in a class of particularly pricey expensive drugs that are commonly prescribed to treat for peptic ulcers, gastritis, gastroesophagul reflux and other related conditions. These medications with other brand name proton pump inhibitor drugs like Prilosec and Protonix.

Ask your doctor to prescribe cheaper generic Dexilant substitute Lansoprazole or Pantoprazole.

Why is Dexilant so expensive?

Dexilant is expensive because it is a brand name medication with few generic alternatives. It typically costs over $300+ per month if not covered by your health insurance but can be found for as little as $2.51 per pill from Canada.

2. Vytorin

Vytorin belongs to a class of expensive drugs known as statins, which lower cholesterol. The only instance in which your doctor might insist you take Vytorin is if you have recently suffered from a heart attack. This is because Vytorin is a straight combination of Simvastatin and another brand name drug called Zetia. If you re taking statins for reduction of heart attack risk, stick to generics.

Ask your doctor to prescribe cheaper generic Vytorin substitute like Simvastatin instead.

3. Accolate (Zafirlukast)

Used for treating asthma, Zafirlukast (accolate) is much pricier than its competitor, montelukast (Singulair). In actuality, montelukast (Singulair) actually works much better for most people because you can take it just once per day and you don’t have to coordinate timing with meals.

Ask your doctor to prescribe cheaper generic Accolate like Montelukast instead.

4. Pristiq

Pristiq is a relative newcomer to the SNRI brand name market and is quite expensive. If you are being treated for fibromyalgia or depression, there are two cheaper and equally effective generic options you can take instead.

Ask your doctor to prescribe cheaper generic Pristiq alernative like venlafaxine or duloxetine instead.

5. Avodart

For patients suffering from enlarged prostate and related issues, the class of drugs commonly prescribed are 5-alpha-reductase inhibitors. Avodart is the most expensive of these. Studies have shown that the less expensive Proscar (finasteride) works just as well.

Ask your doctor to prescribe cheaper generic for Avodart like Finasteride instead.

eDrugSearch - save on medication costs and get free drug coupons

6. Benicar

Benicar is in a class of expensive drugs called angiotensin receptor blockers (ARB). This class, used to treat high blood pressure, offers a number of very effective generics, some of which also come with fewer side effects.

Ask your doctor to prescribe cheaper Benicar generics like valsartan or losartan instead.

7. Vimovo

Vimovo is very expensive, but underneath the fancy brand name you find naproxen and esomeprazole.

Ask your doctor to prescribe 20mg tablets of esomeprazole and 500 mg tablets of naproxen instead. Take the two together to cut your costs in half.

8. Bystolic

Bystolic is commonly prescribed as a beta blocker for high blood pressure. What most patients don’t know is that it is just one of three options that can be successfully used to increase survival rate for heart failure.

Ask your doctor to prescribe cheaper generic drugs such as metoprolol and carvedilol instead.

9. Pataday

For allergy sufferers and those with red itchy eyes, the brand name expensive drugs Pataday and Patanol is very commonly prescribed. But a cheaper and equally good option is azelastine (Optivar).

Ask your doctor to prescribe cheaper Pataday generic like Azelastine instead.

People often ask – Why is Pataday so expensive? While Pataday does provide relief from seasonal allergies it does come with a high price tag that can leave people searching for a lower-cost alternative. By getting monthly medications like Pataday directly from Canadian pharmacies consumers can save a considerable amount on their monthly costs.

10. Celebrex (Celecoxib)

Celebrex (celecoxib) is a very well known and popular arthritis medication in the class of expensive drugs used to treat rheumatoid arthritis and osteoarthritis, even the recent introduction of a generic version has not affected the brand name price (or people’s willingness to pay for it). But there is another lesser known Cox-2 inhibitor option called Mobic (meloxicam) that works just as well and is much cheaper.

Ask your doctor to prescribe doctor to prescribe cheaper generic alternatives for Celebrex like meloxicam instead.


eDrugSearch is a free online drug price comparison search engine. Founded in 2007, eDrugSearch’s mission is simple: to help you find the lowest cost medication that will meet your needs.

If your medication costs are eating into your monthly budget, eDrugSearch can help! Be sure to contact to compare drug prices and save 50-90% off your medications costs.

About Cary Byrd

eDrugSearch founder, Cary Byrd, has been called an “e-health innovator” by MarketIntellNow, interviewed by top pharmaceutical industry journalists, invited to Matthew Holt’s Health 2.0 Conference and a Consumer Report's health summit, and highlighted on numerous health blogs.

Top 10 Expensive Drugs With Cheaper Alternatives

0 thoughts on “Top 10 Expensive Drugs With Cheaper Alternatives

  • Linda Rexroth says:

    Thanks for your information.
    Unfortunately I am Chemical sensitive and
    Wish I could have ability to get off prescription drugs.
    The brand prescription drugs I take is what I can
    All of my Brand name prescriptions have increased in price since Feb./2016.
    Especially Dexilant 60 mg/ 3 month supply
    Is now $322.?

  • Hey Linda, Thank you for sharing your sharing. I hope this article has helped you cut your prescription drug costs. Click the drug name links above (like Dexilant) so that you can quickly compare costs and see that you can save 50-90% on all your medication. Drug prices continue to rise every year so please be sure to use to find the lowest prices!

    If you need anything else or have any questions feel free to reply to this comment and I will get back with you ASAP.

  • Peggy Granberg says:

    I am on Bupropion & Viibryd. I am wanting to know what a substitute for Viibryd as the cost is $675.00 (give or take a $1.00 or 2) &I pay $325.00. Yes, I realize my Ins pays anout 1/2 but since I am now on Social Security, I realy can’t afford this. The combination of these meds has worked very well but if I could get an equivlent of Viibryd that is as.effective but less expensive I would be much happier.

      • I was just prescribe Ranexa and will pay $581 co-pay I will be in the donut hole long before the end of the year. I can’t use their coupon card since I am on Medicare. I am also on Brilinta another expensive drug at $454 for 90 days. Any suggestions there?

    • I was paying $50 for a 30 day script (60 pills- 2x a day) for my Ranexa thru my employer insurance (UPMC Advantage) and getting it at Rite Aid. I switched to the mail option (Express Scripts) and its now $100 for a 90 day supply (180 pills). Saving $50 bucks but…still … That’s the best I can come up with at this point… “patiently” waiting for a generic option to be released… still too much $$ for my budget… (just an admin… tryin’ to stay alive)

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